The B7: CD28 family and friends: Unraveling coinhibitory interactions
KP Burke, A Chaudhri, GJ Freeman, AH Sharpe - Immunity, 2024 - cell.com
Immune responses must be tightly regulated to ensure both optimal protective immunity and
tolerance. Costimulatory pathways within the B7: CD28 family provide essential signals for …
tolerance. Costimulatory pathways within the B7: CD28 family provide essential signals for …
CD28 co-stimulation: novel insights and applications in cancer immunotherapy
MT Lotze, SH Olejniczak, D Skokos - Nature Reviews Immunology, 2024 - nature.com
Substantial progress in understanding T cell signalling, particularly with respect to T cell co-
receptors such as the co-stimulatory receptor CD28, has been made in recent years. This …
receptors such as the co-stimulatory receptor CD28, has been made in recent years. This …
[HTML][HTML] Cellular and molecular signaling towards T cell immunological self-tolerance
F Carbone, C Russo, A Colamatteo, C La Rocca… - Journal of Biological …, 2024 - Elsevier
The binding of a cognate antigen to T cell receptor (TCR) complex triggers a series of
intracellular events controlling T cell activation, proliferation and differentiation. Upon TCR …
intracellular events controlling T cell activation, proliferation and differentiation. Upon TCR …
CD8+ T cell-based cancer immunotherapy
Y Chen, D Yu, H Qian, Y Shi, Z Tao - Journal of Translational Medicine, 2024 - Springer
The immune system in humans is a defense department against both exogenous and
endogenous hazards, where CD8+ T cells play a crucial role in opposing pathological …
endogenous hazards, where CD8+ T cells play a crucial role in opposing pathological …
Prolonged T–DC macro-clustering within lymph node microenvironments initiates Th2 differentiation in a site-specific manner
MR Lyons-Cohen - 2023 - search.proquest.com
Abstract T helper 2 (Th2) responses protect against pathogens while also driving allergic
inflammation, yet how large-scale Th2 responses are generated in tissue context remains …
inflammation, yet how large-scale Th2 responses are generated in tissue context remains …