Peripheral arterial disease (PAD) is caused by occlusive atherosclerosis in a vascular bed
other than the heart. The lower extremity is the most-common location for PAD. Critical limb …

Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

In skeletal muscle, growth of capillaries is an important adaptation to exercise training that
secures adequate diffusion capacity for oxygen and nutrients even at high‐intensity exercise …

Background Altered expression levels and structural variations in the vascular endothelial
growth factor (VEGF) have been found to play important roles in cancer development and to …

Peripheral arterial disease (PAD) is a common vascular disease that reduces blood flow
capacity to the legs of patients. PAD leads to exercise intolerance that can progress in …

Angiogenesis is a critical step of wound healing, and its failure leads to chronic wounds. The
idea of restoring blood flow to the damaged tissues by promoting neo-angiogenesis is …

Peripheral arterial disease (PAD) is a major health care problem. There have been limited
advances in medical therapies, and a huge burden of symptomatic patients with intermittent …

BPC 157, a pentadecapeptide with extensive healing effects, has recently been suggested
to contribute to angiogenesis. However, the underlying mechanism is not yet clear. The …

Angiogenesis is a highly regulated multiscale process that involves a plethora of cells, their
cellular signal transduction, activation, proliferation, differentiation, as well as their …

Therapeutic vascular endothelial growth factor (VEGF) replenishment has met with limited
success for the management of critical limb-threatening ischemia. To improve outcomes of …