Early identification of genetic risk factors for complex diseases can enable timely
interventions and prevent serious outcomes, including mortality. While the genetics …

This scoping review of population-based epidemiological studies was done to provide
background information on the prevalences and distribution of psychiatric disorders in Africa …

Background A key ethical question in genomics research relates to whether individual
genetic research results should be disclosed to research participants and if so, which results …

Background The two recent simultaneous developments of high-throughput sequencing and
increased computational power have brought bioinformatics to the forefront as an important …

Genetic variation in CYP2B6 and CYP2A6 is known to impact interindividual response to
antiretrovirals, nicotine, and bupropion, among other drugs. However, the full catalogue of …

The feedback of individual results of genomics research is an ethical issue. However, which
genetic results African participants would like to receive and why, remains unclear. A …

Background. The Human Health and Heredity (H3Africa) Consortium continues to generate
large amounts of genomic data leading to new insights into health and disease among …

Despite the poor genomics research capacity in Africa, efforts have been made to empower
African scientists to get involved in genomics research, particularly that involving African …

Abstract Background In Africa, health practitioners and the current knowledge of the public
on genetics and genomics is still very low and yet this has potential to reduce the burden of …

Developing a complex collaborative program across multiple African countries,
characterized by a diversity of government models, laws, cultures and norms, resources and …