The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

[HTML][HTML] BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression

S Peng, W Li, L Lv, Z Zhang, X Zhan - Discovery medicine, 2018 - discoverymedicine.com
Schizophrenia and major depression disorders, both being of pathological synaptogenesis,
are the most common psychiatric disorders worldwide. These diseases, if not treated …

Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia

BC Ho, NC Andreasen, S Ziebell… - Archives of general …, 2011 - jamanetwork.com
Context Progressive brain volume changes in schizophrenia are thought to be due
principally to the disease. However, recent animal studies indicate that antipsychotics, the …

Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia

NC Andreasen, P Nopoulos, V Magnotta, R Pierson… - Biological …, 2011 - Elsevier
BACKGROUND: Schizophrenia has a characteristic onset during adolescence or young
adulthood but also tends to persist throughout life. Structural magnetic resonance studies …

Epigenetic regulation of the BDNF gene: implications for psychiatric disorders

F Boulle, DLA Van Den Hove, SB Jakob… - Molecular …, 2012 - nature.com
Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in
the course and development of various neurological and psychiatric disorders. In addition …

[HTML][HTML] A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation

M Aas, P Dazzan, V Mondelli, I Melle… - Frontiers in …, 2014 - frontiersin.org
Objective: To carry out a systematic review of the literature addressing cognitive functions in
first-episode psychosis (FEP), divided into domains. Although this is not a full “cognitive …

Schizophrenia,“just the facts”: what we know in 2008: part 1: overview

R Tandon, MS Keshavan, HA Nasrallah - Schizophrenia research, 2008 - Elsevier
For every disorder, there is a set of established findings and accepted constructs upon which
further understanding is built. The concept of schizophrenia as a disease entity has been …

Brain-derived neurotrophic factor and schizophrenia

P Di Carlo, G Punzi, G Ursini - Psychiatric genetics, 2019 - journals.lww.com
The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes
neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the …

[HTML][HTML] BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, and memory

R Nieto, M Kukuljan, H Silva - Frontiers in psychiatry, 2013 - frontiersin.org
Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been related not only
to neurodevelopment and neuroprotection, but also to synapse regulation, learning, and …

The role of BDNF in the pathophysiology and treatment of schizophrenia

G Favalli, J Li, P Belmonte-de-Abreu, AHC Wong… - Journal of psychiatric …, 2012 - Elsevier
Brain Derived Neurotrophic Factor (BDNF) has been associated with the pathophysiology of
schizophrenia (SCZ). However, it remains unclear whether alterations in BDNF observed in …