The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …
[HTML][HTML] BDNF as a biomarker in diagnosis and evaluation of treatment for schizophrenia and depression
Schizophrenia and major depression disorders, both being of pathological synaptogenesis,
are the most common psychiatric disorders worldwide. These diseases, if not treated …
are the most common psychiatric disorders worldwide. These diseases, if not treated …
Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia
BC Ho, NC Andreasen, S Ziebell… - Archives of general …, 2011 - jamanetwork.com
Context Progressive brain volume changes in schizophrenia are thought to be due
principally to the disease. However, recent animal studies indicate that antipsychotics, the …
principally to the disease. However, recent animal studies indicate that antipsychotics, the …
Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia
BACKGROUND: Schizophrenia has a characteristic onset during adolescence or young
adulthood but also tends to persist throughout life. Structural magnetic resonance studies …
adulthood but also tends to persist throughout life. Structural magnetic resonance studies …
Epigenetic regulation of the BDNF gene: implications for psychiatric disorders
F Boulle, DLA Van Den Hove, SB Jakob… - Molecular …, 2012 - nature.com
Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in
the course and development of various neurological and psychiatric disorders. In addition …
the course and development of various neurological and psychiatric disorders. In addition …
[HTML][HTML] A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation
Objective: To carry out a systematic review of the literature addressing cognitive functions in
first-episode psychosis (FEP), divided into domains. Although this is not a full “cognitive …
first-episode psychosis (FEP), divided into domains. Although this is not a full “cognitive …
Schizophrenia,“just the facts”: what we know in 2008: part 1: overview
R Tandon, MS Keshavan, HA Nasrallah - Schizophrenia research, 2008 - Elsevier
For every disorder, there is a set of established findings and accepted constructs upon which
further understanding is built. The concept of schizophrenia as a disease entity has been …
further understanding is built. The concept of schizophrenia as a disease entity has been …
Brain-derived neurotrophic factor and schizophrenia
P Di Carlo, G Punzi, G Ursini - Psychiatric genetics, 2019 - journals.lww.com
The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes
neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the …
neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the …
[HTML][HTML] BDNF and schizophrenia: from neurodevelopment to neuronal plasticity, learning, and memory
R Nieto, M Kukuljan, H Silva - Frontiers in psychiatry, 2013 - frontiersin.org
Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin that has been related not only
to neurodevelopment and neuroprotection, but also to synapse regulation, learning, and …
to neurodevelopment and neuroprotection, but also to synapse regulation, learning, and …
The role of BDNF in the pathophysiology and treatment of schizophrenia
G Favalli, J Li, P Belmonte-de-Abreu, AHC Wong… - Journal of psychiatric …, 2012 - Elsevier
Brain Derived Neurotrophic Factor (BDNF) has been associated with the pathophysiology of
schizophrenia (SCZ). However, it remains unclear whether alterations in BDNF observed in …
schizophrenia (SCZ). However, it remains unclear whether alterations in BDNF observed in …