Application of nanoscale metal–organic frameworks in tumor immunotherapy

XX Zeng, JS Lu, DW Ma, YT Huang, L Chen, G Wang… - Rare Metals, 2024 - Springer
Immunotherapy has attracted wide attention because it can not only kill tumor cells but also
effectively prevent tumor recurrence. However, due to the poor efficacy of the monotherapy …

Anaphylatoxin receptor promiscuity for commonly used complement C5a peptide agonists

XX Li, RJ Clark, TM Woodruff - International Immunopharmacology, 2021 - Elsevier
The complement system is an essential component of innate immunity. Its activation
generates the effector cleavage proteins, anaphylatoxins C3a and C5a, that exert activity by …

Surface modification of biodegradable microparticles with the novel host-derived immunostimulant CPDI-02 significantly increases short-term and long-term mucosal …

JE Parriott, JP Stewart, DD Smith, SM Curran… - Pharmaceutics, 2022 - mdpi.com
Generating long-lived mucosal and systemic antibodies through respiratory immunization
with protective antigens encapsulated in nanoscale biodegradable particles could …

The Development and In Vivo Immunologic Assessment of Biodegradable Microparticles Incorporating CPDI-02 and Mucosal Protein Vaccine

JE Parriott - 2022 - digitalcommons.unmc.edu
Encapsulation in biodegradable microparticles (MPs) is a promising approach to increase
the efficacy of intranasally administered protein vaccines. The generation of long-lived …

The Formation and Application of Polymeric Micro-and Nanoparticles

S White, JP Stewart, SM Curran, DD Smith, JA Vetro - 2022 - digitalcommons.unmc.edu
Nano-and microparticles are used in the pharmaceutical industry for sustained release drug
delivery systems. For example, polymeric particles are currently used as an FDA-approved …