Cryptococcal meningitis (CM) is a global threat with significant attributable morbidity and
mortality. Information on microfluidic detection for CM diagnosis is still limited. We developed …

Background Cryptococcosis is a devastating opportunistic infection in immunocompromised
individuals, primarily in people living with HIV/AIDS. This study evaluated a protocol for the …

Importance Microbial keratitis (MK) is a common cause of unilateral visual impairment,
blindness, and eye loss in low-income and middle-income countries. There is an urgent …

Abstract Background Cryptococcal antigen (CrAg) screening and treatment with preemptive
fluconazole reduces the incidence of clinically evident cryptococcal meningitis in individuals …

Abstract Purpose of Review Neurosarcoidosis is a rare manifestation of sarcoidosis that is
challenging to diagnose. Biopsy confirmation of granulomas is not sufficient, as other …

Background Early diagnosis of HIV infection and early initiation of ART before
immunosuppression is the most important strategy to reduce the incidence of CM and CM …

Objectives Metagenomic next-generation sequencing (mNGS) has been applied more and
more widely for the diagnosis of infectious diseases, but its performance in the diagnosis of …

Introduction. In recent years, metagenomic next-generation sequencing (mNGS) has
become widely used in medical microbiology to detect pathogen infection. Aim. We aimed to …

Aim Acute meningitis encompasses bacterial, viral (aseptic), fungal, tuberculous, and
carcinomatous meningitis. The rate and risks of mortality in each type remain uncertain. This …

Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC)
are a major cause of fungal meningitis in immunocompromised individuals. As with other …