Peptide-based agents for cancer treatment: current applications and future directions

NTT Nhàn, T Yamada, KH Yamada - International Journal of Molecular …, 2023 - mdpi.com
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …

Imaging biomarkers for clinical applications in neuro-oncology: current status and future perspectives

FY Chiu, Y Yen - Biomarker Research, 2023 - Springer
Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

Multimeric RGD-based strategies for selective drug delivery to tumor tissues

J Cossu, F Thoreau, D Boturyn - Pharmaceutics, 2023 - mdpi.com
RGD peptides have received a lot of attention over the two last decades, in particular to
improve tumor therapy through the targeting of the αVβ3 integrin receptor. This review …

Radionuclide imaging and therapy directed towards the tumor microenvironment: A multi-cancer approach for personalized medicine

CD van der Heide, SU Dalm - European Journal of Nuclear Medicine and …, 2022 - Springer
Targeted radionuclide theranostics is becoming more and more prominent in clinical
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …

Systematic review: targeted molecular imaging of angiogenesis and its mediators in rheumatoid arthritis

F Khodadust, A Ezdoglian, MM Steinz… - International journal of …, 2022 - mdpi.com
Extensive angiogenesis is a characteristic feature in the synovial tissue of rheumatoid
arthritis (RA) from a very early stage of the disease onward and constitutes a crucial event …

RGD peptide in cancer targeting: Benefits, challenges, solutions, and possible integrin–RGD interactions

H Javid, MA Oryani, N Rezagholinejad… - Cancer …, 2024 - Wiley Online Library
RGD peptide can be found in cell adhesion and signaling proteins, such as fibronectin,
vitronectin, and fibrinogen. RGD peptides' principal function is to facilitate cell adhesion by …

[HTML][HTML] Lasso peptide microcin J25 variant containing RGD motif as a PET probe for integrin av ß 3 in tumor imaging

K Mohri, KPH Nhat, M Zouda, S Warashina… - European Journal of …, 2023 - Elsevier
Abstract Microcin J25 (MccJ25), a lasso peptide, has a unique 3-D interlocked structure that
provides high stability under acidic conditions, at high temperatures, and in the presence of …

Peptide therapeutics in the management of metastatic cancers

D Bose, L Roy, S Chatterjee - RSC advances, 2022 - pubs.rsc.org
Cancer remains a leading health concern threatening lives of millions of patients worldwide.
Peptide-based drugs provide a valuable alternative to chemotherapeutics as they are highly …

Development of a Novel Peptide-Based PET Tracer [68Ga]Ga-DOTA-BP1 for BCMA Detection in Multiple Myeloma

L Song, S Jiang, Q Yang, W Huang, Y Qiu… - Journal of Medicinal …, 2024 - ACS Publications
B-cell maturation antigen (BCMA) has emerged as a promising tumor marker for the
diagnosis and treatment of multiple myeloma. The noninvasive and rapid detection of BCMA …

Nanoparticle-based radioconjugates for targeted imaging and therapy of prostate cancer

A Lankoff, M Czerwińska, M Kruszewski - Molecules, 2023 - mdpi.com
Prostate cancer is the second most frequent malignancy in men worldwide and the fifth
leading cause of death by cancer. Although most patients initially benefit from therapy, many …