Flavonoids have many positive pharmacological properties, such as antioxidant, antitumor,
and anti-inflammatory activities. However, factors such as low water solubility and low …

This work developed immediate-release hot melt extruded pellets containing the poorly
aqueous soluble drug Indomethacin with five different screw configurations for oral …

Extrusion-based bioprinting (EBB) is a biofabrication technique that has been widely used
by researchers in the last two decades, mainly due to its versatility, ease to use, and low …

As a promising strategy, amorphous solid dispersion has been extensively employed in
improving the oral bioavailability of insoluble drugs. Despite the numerous advantages, the …

Amorphous solid dispersions (ASD) are one of the most adopted technologies for improving
the solubility of novel molecules. Formulation of ASDs using solvent free methods such as …

This manuscript represents the view of the Dissolution Working Group of the IQ Consortium
on the challenges of and recommendations on solubility measurements and development of …

The application of drugs in the amorphous state is one way to improve their bioavailability.
As such, the determination of the optimal conditions for production and the assessment of …

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active
pharmaceutical ingredient (API) and small molecule excipients. The properties of these …

Orodispersible Films (ODFs) are drug delivery systems manufactured with a wide range of
methods on a big scale or for customized medicines and small-scale pharmacy. Both ODFs …

The physical properties of many modern multi-component materials are determined by their
internal microstructure. Tools capable of characterizing complex nanoscale architectures in …