Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

Caffeic acid and diseases—Mechanisms of action

N Pavlíková - International Journal of Molecular Sciences, 2022 - mdpi.com
Caffeic acid belongs to the polyphenol compounds we consume daily, often in the form of
coffee. Even though it is less explored than caffeic acid phenethyl ester, it still has many …

Therapeutic potential of plant phenolic acids in the treatment of cancer

M Abotaleb, A Liskova, P Kubatka, D Büsselberg - Biomolecules, 2020 - mdpi.com
Globally, cancer is the second leading cause of death. Different conventional approaches to
treat cancer include chemotherapy or radiotherapy. However, these are usually associated …

Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer

S Mirzaei, MH Gholami, A Zabolian, H Saleki… - Pharmacological …, 2021 - Elsevier
As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Caffeic acid attenuates neuroinflammation and cognitive impairment in streptozotocin-induced diabetic rats: Pivotal role of the cholinergic and purinergic signaling …

MFV Castro, CE Assmann, N Stefanello… - The Journal of …, 2023 - Elsevier
The present study evaluated the effect of caffeic acid (CA) on behavioral learning and
memory tasks in the diabetic state. We also evaluated the effect of this phenolic acid on the …

[HTML][HTML] Chemopreventive and chemotherapeutic effect of propolis and its constituents: a mini-review

HF Chiu, YC Han, YC Shen… - Journal of Cancer …, 2020 - ncbi.nlm.nih.gov
Propolis is a bee wax rich in various phytocomponents and traditionally used to treat various
ailments. Propolis is reported to possess an array of biological properties including anti …

The potential of caffeic acid lipid nanoparticulate systems for skin application: in vitro assays to assess delivery and antioxidant effect

SS Hallan, M Sguizzato, M Drechsler, P Mariani… - Nanomaterials, 2021 - mdpi.com
The object of this study is a comparison between solid lipid nanoparticles and ethosomes for
caffeic acid delivery through the skin. Caffeic acid is a potent antioxidant molecule whose …

Phenolic acids-mediated regulation of molecular targets in Ovarian Cancer: current understanding and future perspectives

N Nazam, NR Jabir, I Ahmad, SA Alharthy, MS Khan… - Pharmaceuticals, 2023 - mdpi.com
Cancer is a global health concern with a dynamic rise in occurrence and one of the leading
causes of mortality worldwide. Among different types of cancer, ovarian cancer (OC) is the …

Recent advances in phenolic metabolites and skin cancer

TD Pop, Z Diaconeasa - International Journal of Molecular Sciences, 2021 - mdpi.com
Skin cancer represents any tumor development from the cutaneous structures within the
epidermis, dermis or subcutaneous tissue, and is considered to be the most prevalent type …