[HTML][HTML] Remodeling the tumor immune microenvironment via siRNA therapy for precision cancer treatment

L Jiang, Y Qi, L Yang, YB Miao, W Ren, H Liu… - Asian Journal of …, 2023 - Elsevier
How to effectively transform the pro-oncogenic tumor microenvironments (TME) surrounding
a tumor into an anti-tumoral never fails to attract people to study. Small interfering RNA …

Nanosized drug delivery systems modulate the immunosuppressive microenvironment to improve cancer immunotherapy

W Yan, T Lang, W Yuan, Q Yin, Y Li - Acta Pharmacologica Sinica, 2022 - nature.com
Immunotherapy that activates immune systems for combating cancer has yielded
considerable clinical benefits recently. However, the immunosuppressive tumor …

Nanocarbon Framework-Supported Ultrafine Mo2C@MoOx Nanoclusters for Photothermal-Enhanced Tumor-Specific Tandem Catalysis Therapy

L Wang, L Zhuang, S He, F Tian, X Yang… - … Applied Materials & …, 2021 - ACS Publications
Recent advances in the synthesis of multifunctional nanomaterials create new opportunities
for the rational design of multimodal chemodynamic therapy (CDT) agents. Precisely …

Cancer phototherapy with nano-bacteria biohybrids

H Lu, L Niu, L Yu, K Jin, J Zhang, J Liu, X Zhu… - Journal of Controlled …, 2023 - Elsevier
The utilization of light for therapeutic interventions, also known as phototherapy, has been
extensively employed in the treatment of a wide range of illnesses, including cancer. Despite …

Construction and applications of DNA-based nanomaterials in cancer therapy

H Qi, Y Xu, P Hu, C Yao, D Yang - Chinese Chemical Letters, 2022 - Elsevier
As a biologically active macromolecule, deoxyribonucleic acid (DNA) has the advantages of
sequence programmability and structure controllability and can accurately transmit …

Assembly of catechol-modified polymer brushes for drug delivery

K Zhao, Z Gao, D Song, P Zhang, J Cui - Polymer Chemistry, 2022 - pubs.rsc.org
Therapeutic nanoparticles (NPs) have shown their potential for biomedical applications (eg,
drug delivery). In this study, we report the synthesis of a bottlebrush block copolymer by ring …

Near-infrared upconversion mesoporous tin dioxide theranostic nanocapsules for synergetic cancer chemophototherapy

L Yang, R Shi, R Zhao, Y Zhu, B Liu… - ACS Applied Materials …, 2022 - ACS Publications
Smart nanotheranostic systems (SNSs) have attracted extensive attention in antitumor
therapy. Nevertheless, constructing SNSs with disease diagnosis ability, improved drug …

Cascade strategy for glucose oxidase-based synergistic cancer therapy using nanomaterials

R He, P Yang, A Liu, Y Zhang, Y Chen… - Journal of Materials …, 2023 - pubs.rsc.org
Nanomaterial-based cancer therapy faces significant limitations due to the complex nature
of the tumor microenvironment (TME). Starvation therapy is an emerging therapeutic …

Injectable Responsive Hydrogel Delivery Platform: Enabling High Tissue Penetration and Sonogenetic‐Like Potentiating Anti‐Tumor Immunotherapy

Z Dai, X Li, Q Chen, Y Zhu, Z Shi… - Advanced Functional …, 2024 - Wiley Online Library
The characteristics of malignant solid tumors with dense extracellular matrix (ECM) and
immunosuppressive microenvironment (IME) seriously restrict the high efficacy and precise …

Application of nano-drug delivery system based on cascade technology in cancer treatment

Y Sun, X Ma, H Hu - International Journal of Molecular Sciences, 2021 - mdpi.com
In the current cancer treatment, various combination therapies have been widely used, such
as photodynamic therapy (PDT) combined with chemokinetic therapy (CDT). However, due …