Human exposure to nonsteroidal estrogens in the environment has recently been proposed
as a risk factor for endocrine disruption and the development of cancers of the breast and …

The Elizabeth River system is an estuary in southeastern Virginia, surrounded by the towns
of Chesapeake, Norfolk, Portsmouth, and Virginia Beach. The river has played important …

Transcriptional activation of the human CYP1A1 gene (coding for cytochrome P450 1A1) is
mediated by the aryl hydrocarbon receptor (AhR). In the present study we have examined …

Error-free lesion bypass and error-prone lesion bypass are important cellular responses to
DNA damage during replication, both of which require a DNA polymerase (Pol). To identify …

DNA lesion bypass is an important cellular response to genomic damage during replication.
Human DNA polymerase η (Polη), encoded by the Xeroderma pigmentosum variant (XPV) …

Polycyclic aromatic hydrocarbons (PAHs), pervasive plus priority emerging pollutants have
the potential to destruct the bionetwork. Therefore, photocatalytic decay of toxic 4-and 5-ring …

REV1 functions in the DNA polymerase ζ mutagenesis pathway. To help understand the role
of REV1 in lesion bypass, we have examined activities of purified human REV1 opposite …

Polycyclic aromatic hydrocarbons (PAHs) are significant environmental pollutants
representing an important risk factor in human cancers. DNA adducts formed by the ultimate …

Polycyclic aromatic hydrocarbons (PAHs) are associated with occupational exposure and
urban atmospheric pollution. Determination of the genotoxic properties of these compounds …

Single Cell Gel Electrophoresis is currently used to investigate the cell response to
genotoxic agents as well as to several biotic and abiotic stresses that lead to oxidative DNA …