Quercetin, a typical flavonoid, possesses diverse biochemical and physiological actions,
including antiplatelet, estrogenic, and anti-inflammatory properties. This review mainly …

Diabetes mellitus is associated to an increased risk of cardiovascular diseases.
Hyperglycemia is an important factor in cardiovascular damage, working through different …

Cardiac autonomic neuropathy (CAN) is an often overlooked and common complication of
diabetes mellitus. CAN is associated with increased cardiovascular morbidity and mortality …

Diabetic cardiomyopathy (DCM) is a cardiac dysfunction which affects approximately 12% of
diabetic patients, leading to overt heart failure and death. However, there is not an efficient …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS, eg nitric oxide, NO) are
well recognised for playing a dual role as both deleterious and beneficial species. ROS and …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Diabetes is associated with increased incidence of heart failure even after controlling for
coronary artery disease and hypertension. Thus, as diabetic cardiomyopathy has become …

Orthostatic hypotension is defined as a fall in BP (ie, 30 mm Hg systolic or 10 mm Hg
diastolic BP) in response to a postural change from supine to standing. 18 Symptoms …

A growing body of evidence suggests that oxidative stress plays a key role in the
pathogenesis of micro-and macrovascular diabetic complications. The increased oxidative …

The high incidence and poor prognosis of heart failure (HF) patients affected with diabetes
(DM) is in part related to a specific cardiac remodeling currently recognized as diabetic …