Neonicotinoid insecticides are widely used in both urban and agricultural settings around
the world. Historically, neonicotinoid insecticides have been viewed as ideal replacements …

The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …

The neurotransmitter acetylcholine (ACh) regulates a diverse array of physiological
processes throughout the body. Despite its importance, cholinergic transmission in the …

Cigarette smoking is the single most important risk factor for the development of
cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in …

Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …

Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

Adolescence encompasses a sensitive developmental period of enhanced clinical
vulnerability to nicotine, tobacco, and e‐cigarettes. While there are sociocultural influences …

Transmission from striatal cholinergic interneurons (CINs) controls dopamine release
through nicotinic acetylcholine receptors (nAChRs) on dopaminergic axons. Anatomical …

COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now
the United States. While the majority of infected cases appear mild, in some cases …