Background Crack-cocaine use is prevalent largely in socio-economically marginalized
populations in the Americas. Its use has been associated with diverse health outcomes, yet …

Brain-derived neurotrophic factor (BDNF) has been found to play roles in many types of
plasticity including drug addiction. Here, we focus on rodent studies over the past two …

Background Brain-derived neurotrophic factor (BDNF) is associated with several
neurodegenerative and psychiatric disorders. It is not clear, however, whether BDNF levels …

Introduction: Cocaine use disorder is a chronic disease with severe consequences and a
high relapse rate. There is a critical need to explore the factors influencing relapse in order …

Rationale An important goal of addiction research is to discover neurobiological markers
that could predict the severity of addiction and help to determine appropriate treatment …

Brain-derived neurotrophic factor (BDNF) and its precursor, proBDNF, are known to
significantly contribute to brain homeostasis, neuroplasticity, and neuronal remodeling …

Brain-derived neurotrophic factor (BDNF) affects synaptic plasticity and neural structure and
plays key roles in learning and memory processes. Recent evidence also points to …

Background Depression symptoms is highly comorbid with methamphetamine (METH)
dependence. Except for the role in the pathophysiology of depression symptoms, brain …

After discovering that addictive drugs alter adult neurogenesis, the potential role of adult-
born hippocampal neurons in drug addiction has become a promising research field, in …

Recent studies have identified biomarkers related to the severity and pathogenesis of
cocaine addiction and common comorbid psychiatric disorders. Monitoring these plasma …