The MET oncogene encodes an unconventional receptor tyrosine kinase with pleiotropic
functions: it initiates and sustains neoplastic transformation when genetically altered …

Cataract, a clouding of the lens, is the most common cause of blindness in the world. It has a
marked impact on the wellbeing and productivity of individuals and has a major economic …

Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

Glutathione (GSH) is a ubiquitous intracellular peptide with diverse functions that include
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …

Chargé, Sophie BP, and Michael A. Rudnicki. Cellular and Molecular Regulation of Muscle
Regeneration. Physiol Rev 84: 209–238, 2004; 10.1152/physrev. 00019.2003.—Under …

Liver zonation, the spatial separation of the immense spectrum of different metabolic
pathways along the liver sinusoids, is fundamental for proper functioning of this organ …

The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or
hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while …

Advanced therapies combating acute and chronic skin wounds are likely to be brought
about using our knowledge of regenerative medicine coupled with appropriately tissue …

LIMB muscles develop from cells that migrate from the somites1, 2. The signal that induces
migration of myogenic precursor cells to the limb emanates from the mesenchyme of the …

GROWTH is one of the fundamental aspects in the development of an organism. Classical
genetic studies have isolated four viable, spontaneous mouse mutants1 disrupted in growth …