The lymphatic vascular system plays a pivotal role in mediating tissue fluid homeostasis and
cancer metastasis, but the molecular mechanisms that regulate its formation and function …

Hepatocyte growth factor (HGF) is the only known growth factor that activates quiescent
satellite cells in skeletal muscle. We hypothesized that local delivery of HGF may enhance …

Primary hepatocytes are commonly used as liver surrogates in toxicology and tissue
engineering fields, therefore, maintenance of functional hepatocytes in vitro is an important …

Cytokines comprise a group of small proteins released from cells in order to influence the
function of other cells. By binding to highly specific cell-surface receptors, they trigger a vast …

Invasive and metastatic potentials of several types of carcinoma cells are regulated through
interactions with host stromal cells, eg, tumor-stromal interactions. Because hepatocyte …

Bone marrow (BM) cells originally include alpha-fetoprotein (AFP)-and c-Met [a receptor for
hepatocyte growth factor (HGF)]-expressing cells. In vitro treatment of BM cells with HGF …

Met, the receptor for hepatocyte growth factor (HGF), is activated in human cancer by both
ligand-dependent and-independent mechanisms. We engineered a soluble Met receptor …

The use of adipose-derived stem/stromal cells (ASCs) for promoting repair of tissues is a
promising potential therapy, but the mechanisms of their action are not fully understood. We …

Hepatocyte growth factor (HGF) is a pleiotropic cytokine that has been extensively studied
over several decades, but was only recently recognized as a key player in mediating …

Hepatocyte growth factor (HGF) plays an important role in many biological events such as
angiogenesis, cell proliferation, anti-fibrosis and antiapoptosis. It is well known that HGF …