[PDF][PDF] Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis

Y Matsuda, K Matsumoto, A Yamada, T Ichida… - …, 1997 - Wiley Online Library
Liver fibrosis/cirrhosis is characterized by hyper‐accumulation of fibrous tissue components
and is commonly observed in later or terminal states of chronic hepatic diseases. In ongoing …

Mechanism of estrogen action: lessons from the estrogen receptor-α knockout mouse

PS Cooke, DL Buchanan, DB Lubahn… - Biology of …, 1998 - academic.oup.com
Estradiol-17β (E2) stimulates uterine and vaginal epithelial proliferation in vivo [1]. E2 also
plays a critical role in other aspects of uterine and vaginal growth and adult function, and it is …

[HTML][HTML] HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor

K Date, K Matsumoto, H Shimura, M Tanaka… - FEBS letters, 1997 - Elsevier
We prepared a specific antagonist for hepatocyte growth factor (HGF) and designated it
HGF/NK4. HGF/NK4 is composed of N-terminal 447 amino acids of the α-chain of HGF, thus …

Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma

C Seidel, M Børset, I Turesson… - Blood, The Journal …, 1998 - ashpublications.org
Serum from 398 myeloma patients at diagnosis and serial samples from 29 patients were
analysed for hepatocyte growth factor (HGF). HGF was elevated at diagnosis in 43% of …

Regulation and clinical implications of corneal epithelial stem cells

SCG Tseng - Molecular biology reports, 1996 - Springer
The corneal epithelium is known to have a rapid self-renewing capacity. The major advance
in the field of cornead epithelial cell biology in the last decade is the establishment of the …

Expression and activation of pro-MMP-2 and pro-MMP-9 during rat liver regeneration

TH Kim, WM Mars, DB Stolz, GK Michalopoulos - Hepatology, 2000 - journals.lww.com
Partial hepatectomy triggers a variety of biological phenomena, which culminate in
regeneration of the liver mass. Hepatocyte proliferation is a major feature of the regenerating …

Simultaneous or delayed administration of hepatocyte growth factor equally represses the fibrotic changes in murine lung injury induced by bleomycin: a morphologic …

M Yaekashiwa, S Nakayama, K Ohnuma… - American journal of …, 1997 - atsjournals.org
Hepatocyte growth factor (HGF) is a humoral mediator of epithelial-mesenchymal
interactions, acting on a variety of epithelial cells as mitogen, motogen, and morphogen …

Cross-talk between the proto-oncogenes Met and Ron

A Follenzi, S Bakovic, P Gual, MC Stella, P Longati… - Oncogene, 2000 - nature.com
Scatter Factors control a complex genetic program known as 'invasive growth'. HGF (Scatter
factor 1) and MSP (Scatter Factor 2) bind to tyrosine kinase receptors encoded by the proto …

Hepatocyte growth factor and its receptor c-met in multiple myeloma

M Borset, H Hjorth-Hansen, C Seidel, A Sundan… - 1996 - ashpublications.org
We have examined whether the hepatocyte growth factor (HGF)/c-met receptor-ligand pair is
expressed in freshly isolated and highly purified myeloma cells and whether HGF can be …

The molecular physiology of liver regeneration following partial hepatectomy

D Mangnall, NC Bird, AW Majeed - Liver international, 2003 - Wiley Online Library
The ability of the liver to regenerate after resection has been known for many years. Two
reports from Germany in the late 1800s probably mark the introduction of the phenomenon …