[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years …
Background Respiratory syncytial virus (RSV) is the most common cause of acute lower
respiratory infection in young children. We previously estimated that in 2015, 33· 1 million …
respiratory infection in young children. We previously estimated that in 2015, 33· 1 million …
Fixed or random effects meta-analysis? Common methodological issues in systematic reviews of effectiveness
Systematic review aims to systematically identify, critically appraise, and summarize all
relevant studies that match predefined criteria and answer predefined questions. The most …
relevant studies that match predefined criteria and answer predefined questions. The most …
Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis
Summary Background In February, 2017, the US Food and Drug Administration approved
the blood infection marker procalcitonin for guiding antibiotic therapy in patients with acute …
the blood infection marker procalcitonin for guiding antibiotic therapy in patients with acute …
Meta-analysis of proportions using generalized linear mixed models
Epidemiologic research often involves meta-analyses of proportions. Conventional two-step
methods first transform each study's proportion and subsequently perform a meta-analysis …
methods first transform each study's proportion and subsequently perform a meta-analysis …
Methods to estimate the between‐study variance and its uncertainty in meta‐analysis
Meta‐analyses are typically used to estimate the overall/mean of an outcome of interest.
However, inference about between‐study variability, which is typically modelled using a …
However, inference about between‐study variability, which is typically modelled using a …
Mind matters: A meta-analysis on parental mentalization and sensitivity as predictors of infant–parent attachment.
Major developments in attachment research over the past 2 decades have introduced
parental mentalization as a predictor of infant–parent attachment security. Parental …
parental mentalization as a predictor of infant–parent attachment security. Parental …
Meta‐analysis using individual participant data: one‐stage and two‐stage approaches, and why they may differ
Meta‐analysis using individual participant data (IPD) obtains and synthesises the raw,
participant‐level data from a set of relevant studies. The IPD approach is becoming an …
participant‐level data from a set of relevant studies. The IPD approach is becoming an …
An extended mixed‐effects framework for meta‐analysis
Standard methods for meta‐analysis are limited to pooling tasks in which a single effect size
is estimated from a set of independent studies. However, this setting can be too restrictive for …
is estimated from a set of independent studies. However, this setting can be too restrictive for …
Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of …
Background The clinical utility of serum procalcitonin levels in guiding antibiotic treatment
decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on …
decisions in patients with sepsis remains unclear. This patient-level meta-analysis based on …
Closing the gap between methodologists and end-users: R as a computational back-end
The R environment provides a natural platform for developing new statistical methods due to
the mathematical expressiveness of the language, the large number of existing libraries, and …
the mathematical expressiveness of the language, the large number of existing libraries, and …