[HTML][HTML] Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of …
M Hou, W Hu, Z Xiu, A Jiang, L Men, K Hao, X Sun… - Molecules, 2019 - mdpi.com
For the full development and utilization of Sophora tonkinensis Gagnep., this study was
primarily intended to established a simple and efficient approach for the preparative …
primarily intended to established a simple and efficient approach for the preparative …
SKI3301, a purified herbal extract from Sophora tonkinensis, inhibited airway inflammation and bronchospasm in allergic asthma animal models in vivo
H Yoo, M Kang, S Pyo, HS Chae, KH Ryu, J Kim… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological relevance Sophora tonkinensis (Leguminosae, ST) is a
traditional herbal plant in Korea and China. Its roots and rhizomes have been used to …
traditional herbal plant in Korea and China. Its roots and rhizomes have been used to …
Current mass spectrometry approaches and challenges for the bioanalysis of traditional Chinese medicines
X Dong, R Wang, X Zhou, P Li, H Yang - Journal of Chromatography B, 2016 - Elsevier
Abstract Traditional Chinese medicines (TCMs) are gaining more and more attentions all
over the world. The focus of TCMs researches were gradually shifted from chemical …
over the world. The focus of TCMs researches were gradually shifted from chemical …
[HTML][HTML] Lack of Correlation between In Vitro and In Vivo Studies on the Inhibitory Effects of (‒)-Sophoranone on CYP2C9 Is Attributable to Low Oral Absorption and …
YF Zheng, SH Bae, Z Huang, SU Chae, SJ Jo, HJ Shim… - Pharmaceutics, 2020 - mdpi.com
(‒)-Sophoranone (SPN) is a bioactive component of Sophora tonkinensis with various
pharmacological activities. This study aims to evaluate its in vitro and in vivo inhibitory …
pharmacological activities. This study aims to evaluate its in vitro and in vivo inhibitory …
[PDF][PDF] In vitro and in vivo human gastric cancer inhibition by Trifolirhizin is facilitated via autophagy, mitochondrial mediated programmed cell death, G2/M phase cell …
K Zhang, W Liu, Z Qu, Q Liu, J Chen, R Tao, Y Deng… - J BUON, 2019 - jbuon.com
Purpose: To investigate the anticancer effects of Trifolirhizin in SNU-5 human gastric cancer
cells along with evaluation of its effects on autophagy, apoptosis, cell cycle phase …
cells along with evaluation of its effects on autophagy, apoptosis, cell cycle phase …
Trifolirhizin relieves renal injury in a diabetic nephropathy model by inducing autophagy and inhibiting oxidative stress through the regulation of PI3K/AKT/mTOR …
Y Xin, X Xu, X Yang, Y Chen, D Zhu - Tropical Journal of Pharmaceutical …, 2022 - ajol.info
Purpose: To evaluate the effects of trifolirhizin on diabetic nephropathy (DN), and the
mechanism of action. Methods: Male db/db mice (8 weeks, n= 24) and age-matched control …
mechanism of action. Methods: Male db/db mice (8 weeks, n= 24) and age-matched control …
Determination of trifolirhizin in rat plasma by UPLC: Application to a pharmacokinetic study
K Ni, X Huang, C Wang, T Ye, G Hu, M Zhou - Journal of Chromatography …, 2015 - Elsevier
In this study, a simple, sensitive, and robust analytical method based on ultra-performance
liquid chromatography (UPLC) has been developed for the determination of trifolirhizin in rat …
liquid chromatography (UPLC) has been developed for the determination of trifolirhizin in rat …
Pharmacokinetic properties of trifolirhizin,(–)-maackiain,(–)-sophoranone and 2-(2, 4-dihydroxyphenyl)-5, 6-methylenedioxybenzofuran after intravenous and oral …
SM Jang, SH Bae, WK Choi, JB Park, D Kim, JS Min… - Xenobiotica, 2015 - Taylor & Francis
SKI3301, a standardized dried 50% ethanolic extracts of Sophora tonkinensis, contains four
marker compounds (trifolirhizin, TF;(–)-maackiain, Maack;(–)-sophoranone, SPN, and (2-(2 …
marker compounds (trifolirhizin, TF;(–)-maackiain, Maack;(–)-sophoranone, SPN, and (2-(2 …