Atrial fibrillation (AF) is a highly prevalent arrhythmia, with substantial associated morbidity
and mortality. There have been significant management advances over the past 2 decades …

Cardiac alternans arises from dynamical instabilities in the electrical and calcium cycling
systems of the heart, and often precedes ventricular arrhythmias and sudden cardiac death …

Rationale: Postoperative atrial fibrillation (POAF) is a common and troublesome
complication of cardiac surgery. POAF is generally believed to occur when postoperative …

Pre-existing Ca 2+ handling abnormalities constitute the arrhythmogenic substrate in
patients developing postoperative atrial fibrillation (POAF), a common complication after …

Atrial fibrillation (AF) is a very common cardiac arrhythmia with an estimated prevalence of
33.5 million patients globally. It is associated with an increased risk of death, stroke and …

Background Malignant ventricular arrhythmia (VA) is a major contributor to sudden cardiac
death (SCD) in patients with pulmonary arterial hypertension (PAH)-induced right heart …

Diastolic Ca 2+ leak due to cardiac ryanodine receptor (RyR2) hyperactivity has been widely
documented in chronic ischemic heart disease (CIHD) and may contribute to ventricular …

Since the clinical use of digitalis as the first pharmacological therapy for atrial fibrillation (AF)
235 years ago in 1785, antiarrhythmic drug therapy has advanced considerably and …

Atrial fibrillation (AF) is the most common clinically relevant arrhythmia in horses, with a
reported prevalence up to 2.5%. The pathophysiology has mainly been investigated in …

The prevalence of atrial fibrillation (AF) is bound to increase globally in the following years,
affecting the quality of life of millions of people, increasing mortality and morbidity, and …