Abstract In 2007, human papillomavirus (HPV) type 16 was finally recognized as a risk
factor, besides smoking and alcohol, for oropharyngeal squamous cell carcinoma (OPSCC) …

Comprehensive genomic analyses have been performed for head and neck squamous cell
carcinoma (HNSCC), revealing a significant rate of NOTCH1 mutations and identifying …

Background Head and neck squamous cell carcinoma (HNSCC) remain a substantial
burden to global health. Cell-free circulating tumour DNA (ctDNA) is an emerging biomarker …

Human papillomavirus (HPV)-negative head and neck squamous cell carcinomas
(HNSCCs) are deadly and common cancers. Recent genomic studies implicate multiple …

The dominant paradigm for HPV carcinogenesis includes integration into the host genome
followed by expression of E6 and E7 (E6/E7). We explored an alternative carcinogenic …

Purpose: Vulvar cancer (VC) can be subclassified by human papillomavirus (HPV) status.
HPV-negative VCs frequently harbor TP53 mutations; however, in-depth analysis of other …

Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth
factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic …

Summary Analysis of The Cancer Genome Atlas and other published data of head and neck
squamous cell carcinoma (HNSCC) reveals somatic alterations of the Hippo-YAP pathway …

The transcription factor CCAAT/enhancer-binding protein alpha (C/EBPα) plays a critical
role during embryogenesis and is thereafter required for homeostatic glucose metabolism …

The four receptor tyrosine kinases (RTKs) within the family of Fibroblast Growth Factor
Receptors (FGFRs) are critical for normal development but also play an enormous role in …