89Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art 89Zr Radiochemistry
S Heskamp, R Raavé, O Boerman… - Bioconjugate …, 2017 - ACS Publications
Immuno-positron emission tomography (immunoPET) with 89Zr-labeled antibodies has
shown great potential in cancer imaging. It can provide important information about the …
shown great potential in cancer imaging. It can provide important information about the …
[HTML][HTML] 89Zr-PET imaging in humans: a systematic review
MS De Feo, M Pontico, V Frantellizzi, F Corica… - Clinical and …, 2022 - Springer
Purpose The remarkable amount of preclinical data achieved on 89 Zr-PET imaging led to a
significant clinical translation, concerning mainly immuno-PET applications. The aim of this …
significant clinical translation, concerning mainly immuno-PET applications. The aim of this …
Alternative Chelator for 89Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)
Zirconium-89 is an effective radionuclide for antibody-based positron emission tomography
(PET) imaging because its physical half-life (78.41 h) matches the biological half-life of IgG …
(PET) imaging because its physical half-life (78.41 h) matches the biological half-life of IgG …
A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies
A squaramide ester derivative of desferrioxamine B (H3DFO) that is compatible with
aqueous solvents and does not induce antibody aggregation is used to attach the …
aqueous solvents and does not induce antibody aggregation is used to attach the …
Equilibrium thermodynamics of macropa complexes with selected metal isotopes of radiopharmaceutical interest
MK Blei, L Waurick, F Reissig, K Kopka… - Inorganic …, 2023 - ACS Publications
To pursue the design of in vivo stable chelating systems for radiometals, a concise and
straightforward method toolbox was developed combining NMR, isothermal titration …
straightforward method toolbox was developed combining NMR, isothermal titration …
Octadentate Picolinic Acid‐Based Bispidine Ligand for Radiometal Ions
The synthesis of the octadentate bispidine ligand bearing two picolinic acid pendant arms
(H2bispa2), and its coordination chemistry with radionuclides relevant for nuclear medicine …
(H2bispa2), and its coordination chemistry with radionuclides relevant for nuclear medicine …
[HTML][HTML] Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152 Tb-DOTATOC
RP Baum, A Singh, M Benešová, C Vermeulen… - Dalton …, 2017 - pubs.rsc.org
The existence of theragnostic pairs of radionuclides allows the preparation of
radiopharmaceuticals for diagnostic and therapeutic purposes. Radiolanthanides, such as …
radiopharmaceuticals for diagnostic and therapeutic purposes. Radiolanthanides, such as …
Exploiting Copper Redox for 19F Magnetic Resonance-Based Detection of Cellular Hypoxia
D Xie, TL King, A Banerjee, V Kohli… - Journal of the American …, 2016 - ACS Publications
We report a pair of fluorinated, redox-active copper complexes for potential use as 19F MRI
contrast agents for detecting cellular hypoxia. Trifluorinated Cu (II) ATSM-F3 displays the …
contrast agents for detecting cellular hypoxia. Trifluorinated Cu (II) ATSM-F3 displays the …
Chelators and metal complex stability for radiopharmaceutical applications
NC Okoye, JE Baumeister, F Najafi Khosroshahi… - Radiochimica …, 2019 - degruyter.com
Diagnostic and therapeutic nuclear medicine relies heavily on radiometal nuclides. The
most widely used and well-known radionuclide is technetium-99m (99mTc), which has …
most widely used and well-known radionuclide is technetium-99m (99mTc), which has …
[HTML][HTML] Targeted α-therapy of prostate cancer using radiolabeled PSMA inhibitors: a game changer in nuclear medicine
R Chakravarty, CM Siamof, A Dash… - American journal of …, 2018 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is one of the most common malignancies in men and is a major
contributor to cancer related deaths worldwide. Metastatic spread and disease progression …
contributor to cancer related deaths worldwide. Metastatic spread and disease progression …