The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …

Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating …

The ongoing pandemic of Coronavirus disease 2019 (COVID-19) is severely challenging
healthcare systems all around the world, with the need to provide intensive care to a …

The pathophysiology of COVID-19–associated thrombosis seems to be multifactorial. We
hypothesized that COVID-19 is accompanied by procoagulant platelets with subsequent …

Sepsis is a complex syndrome with a high incidence, increasing by 8.7% annually over the
last 20 years. Coagulopathy is a leading factor associated with mortality in patients with …

Platelets have emerged as key inflammatory cells implicated in the pathology of sepsis, but
their contributions to rapid clinical deterioration and dysregulated inflammation have not …

In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …

The acute respiratory illnesses caused by severe acquired respiratory syndrome corona
Virus-2 (SARS-CoV-2) is a global health emergency, involving more than 8.6 million people …

Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …

Sepsis represents an important global health burden due to its high mortality and morbidity.
The rapid detection of sepsis is crucial in order to prevent adverse outcomes and reduce …