Pain is a personalized event or body alarm system that can limit a patient's activities and
lead to negative repercussions. The commercially available conventional treatment …

Arthritis is a general term for various types of inflammatory joint diseases. The most common
clinical conditions are mainly represented by rheumatoid arthritis and osteoarthritis, which …

Conventional RA treatments required prolonged therapy courses that have been
accompanied with numerous side effects impairing the patient's quality of life. Therefore …

Tofacitinib (TF) is a selective oral jakanib approved by the USFDA for the treatment of
rheumatoid arthritis (RA). To overcome the adverse effects of orally administered TF, topical …

Skin cancer is one of leading cancers globally, divided into two major categories including
melanoma and nonmelanoma. Skin cancer is a global concern with an increasing trend …

In this study, a dosage form consisting of dissolving (D) microneedles (M) and an adhesive
(A) transdermal patch (P; DMAP) was designed and pre-clinically evaluated for the treatment …

Despite growing prevalence and incidence, the management of gout remains suboptimal.
The intermittent nature of the gout makes the long-term urate-lowering therapy (ULT) …

Rheumatoid Arthritis (RA) is a chronic, inflammatory, auto-immune disease that is majorly
associated with the degradation of the synovial linings of the joints. It is a progressive …

Rheumatoid arthritis is an inflammatory disease, and pyroptosis is a form of death
associated with an inflammatory response. Pyroptosis, which occurs in synovial and …

Rheumatoid arthritis (RA) is an autoimmune disease of synovial inflammation that affects
populations worldwide. Transdermal drug delivery systems for treating RA have increased …