Near-infrared spectroscopy and skeletal muscle oxidative function in vivo in health and disease: a review from an exercise physiology perspective

B Grassi, V Quaresima - Journal of biomedical optics, 2016 - spiedigitallibrary.org
In most daily activities related to work or leisure, the energy for muscle work substantially
comes from oxidative metabolism. Functional limitations or impairments of this metabolism …

Interaction of factors determining critical power

RP Goulding, S Marwood - Sports medicine, 2023 - Springer
The physiological determinants of high-intensity exercise tolerance are important for both
elite human performance and morbidity, mortality and disease in clinical settings. The …

Influence of muscle metabolic heterogeneity in determining the V̇o2p kinetic response to ramp-incremental exercise

DA Keir, AP Benson, LK Love… - Journal of Applied …, 2016 - journals.physiology.org
The pulmonary O2 uptake (V̇o2p) response to ramp-incremental (RI) exercise increases
linearly with work rate (WR) after an early exponential phase, implying that a single time …

The influence of metabolic and circulatory heterogeneity on the expression of pulmonary oxygen uptake kinetics in humans

DA Keir, TC Robertson, AP Benson… - Experimental …, 2016 - Wiley Online Library
New Findings What is the central question of this study? The finding that pulmonary oxygen
uptake () kinetics on transition to moderate exercise is invariant and exponential is …

Near‐infrared spectroscopy of superficial and deep rectus femoris reveals markedly different exercise response to superficial vastus lateralis

S Koga, D Okushima, TJ Barstow… - Physiological …, 2017 - Wiley Online Library
To date our knowledge of skeletal muscle deoxygenation as measured by near‐infrared
spectroscopy (NIRS) is predicated almost exclusively on sampling of superficial muscle (s) …

Constructing quasi-linear V̇o2 responses from nonlinear parameters

SL Wilcox, RM Broxterman… - Journal of Applied …, 2016 - journals.physiology.org
Oxygen uptake (V̇o2) kinetics have been shown to be governed by a nonlinear control
system across a range of work rates. However, the linearity of the V̇o2 response to ramp …

Separate and combined effects of a 10-d exposure to hypoxia and inactivity on oxidative function in vivo and mitochondrial respiration ex vivo in humans

D Salvadego, ME Keramidas… - Journal of Applied …, 2016 - journals.physiology.org
An integrative evaluation of oxidative metabolism was carried out in 9 healthy young men
(age, 24.1±1.7 yr mean±SD) before (CTRL) and after a 10-day horizontal bed rest carried …

Relationship between muscle venous blood oxygenation and near-infrared spectroscopy: quantitative analysis of the Hb and Mb contributions

B Koirala, A Concas, Y Sun… - Journal of Applied …, 2023 - journals.physiology.org
A linear relationship between skeletal muscle venous (C ven T) and oxygenated (ΔHbMbO2,
N) or deoxygenated (ΔHHbMbN) near-infrared spectroscopy (NIRS) signals suggest a main …

Changes in whole tissue heme concentration dissociates muscle deoxygenation from muscle oxygen extraction during passive head-up tilt

A Adami, S Koga, N Kondo… - Journal of Applied …, 2015 - journals.physiology.org
Skeletal muscle deoxygenated hemoglobin and myoglobin concentration ([HHb]), assessed
by near-infrared spectroscopy (NIRS), is commonly used as a surrogate of regional O2 …

“Work‐to‐Work” exercise slows pulmonary oxygen uptake kinetics, decreases critical power, and increases W'during supine cycling

RP Goulding, DM Roche, S Marwood - Physiological Reports, 2018 - Wiley Online Library
We have previously demonstrated that the phase II time constant of pulmonary oxygen
uptake kinetics () is an independent determinant of critical power (CP) when O2 availability …