[HTML][HTML] Duchenne muscular dystrophy: Disease mechanism and therapeutic strategies
A Bez Batti Angulski, N Hosny, H Cohen… - Frontiers in …, 2023 - frontiersin.org
Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …
[HTML][HTML] CRISPR technologies for the treatment of Duchenne muscular dystrophy
E Choi, T Koo - Molecular therapy, 2021 - cell.com
The emerging clustered regularly interspaced short palindromic repeats (CRISPR)-mediated
genome editing technologies have progressed remarkably in recent years, opening up the …
genome editing technologies have progressed remarkably in recent years, opening up the …
Advances in CRISPR/Cas9 genome editing for the treatment of muscular dystrophies
S Fatehi, RM Marks, MJ Rok, L Perillat… - Human Gene …, 2023 - liebertpub.com
Muscular dystrophies (MDs) comprise a diverse group of inherited disorders characterized
by progressive muscle loss and weakness. Given the genetic etiology underlying MDs …
by progressive muscle loss and weakness. Given the genetic etiology underlying MDs …
[HTML][HTML] CRISPR-based therapeutic gene editing for Duchenne muscular dystrophy: advances, challenges and perspectives
G Chen, T Wei, H Yang, G Li, H Li - Cells, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease arising from loss-
of-function mutations in the dystrophin gene and characterized by progressive muscle …
of-function mutations in the dystrophin gene and characterized by progressive muscle …
[HTML][HTML] Targeting Nrf2 for the treatment of Duchenne muscular dystrophy
Imbalances in redox homeostasis can result in oxidative stress, which is implicated in
various pathological conditions including the fatal neuromuscular disease Duchenne …
various pathological conditions including the fatal neuromuscular disease Duchenne …
Role of CRISPR/Cas9 in the treatment of Duchenne muscular dystrophy and its delivery strategies
Duchenne muscular dystrophy (DMD) is a neuromuscular disorder brought on by mutations
in the DMD gene, which prevent muscle cells from expressing the dystrophin protein …
in the DMD gene, which prevent muscle cells from expressing the dystrophin protein …
[PDF][PDF] RETRACTED: Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell
S Shojaei Baghini, ZR Gardanova, AO Zekiy… - … in Bioengineering and …, 2021 - frontiersin.org
During recent years, clustered regularly interspaced short palindromic repeat
(CRISPR)/CRISPR-associated protein 9 (Cas9) technologies have been noticed as a rapidly …
(CRISPR)/CRISPR-associated protein 9 (Cas9) technologies have been noticed as a rapidly …
[HTML][HTML] Application of CRISPR/Cas9 system in establishing large animal models
Y Lin, J Li, C Li, Z Tu, S Li, XJ Li, S Yan - Frontiers in Cell and …, 2022 - frontiersin.org
The foundation for investigating the mechanisms of human diseases is the establishment of
animal models, which are also widely used in agricultural industry, pharmaceutical …
animal models, which are also widely used in agricultural industry, pharmaceutical …
Developments in reading frame restoring therapy approaches for Duchenne muscular dystrophy
AFE Schneider, A Aartsma-Rus - Expert opinion on biological …, 2021 - Taylor & Francis
Introduction Exon skipping compounds restoring the dystrophin transcript reading frame
have received regulatory approval for Duchenne muscular dystrophy (DMD). Recently, focus …
have received regulatory approval for Duchenne muscular dystrophy (DMD). Recently, focus …
[PDF][PDF] Modern sustainable techniques for enhancing crop production
Due to increasing population, the availability of arable land is declining every year and
environmental factors like global warming, flood, drought, soil toxicity (due to increased use …
environmental factors like global warming, flood, drought, soil toxicity (due to increased use …