Human dorsal root ganglia
RV Haberberger, C Barry, N Dominguez… - Frontiers in cellular …, 2019 - frontiersin.org
Sensory neurons with cell bodies situated in dorsal root ganglia convey information from
external or internal sites of the body such as actual or potential harm, temperature or muscle …
external or internal sites of the body such as actual or potential harm, temperature or muscle …
Plant/algal polysaccharides extracted by microwave: A review on hypoglycemic, hypolipidemic, prebiotic, and immune-stimulatory effect
M Mirzadeh, AK Lelekami, L Khedmat - Carbohydrate Polymers, 2021 - Elsevier
Microwave-assisted extraction (MAE) is an emerging technology to obtain polysaccharides
with an extensive spectrum of biological characteristics. In this study, the hypoglycemic …
with an extensive spectrum of biological characteristics. In this study, the hypoglycemic …
Atomistic simulations of membrane ion channel conduction, gating, and modulation
Membrane ion channels are the fundamental electrical components in the nervous system.
Recent developments in X-ray crystallography and cryo-EM microscopy have revealed what …
Recent developments in X-ray crystallography and cryo-EM microscopy have revealed what …
Neurotoxins acting at synaptic sites: A brief review on mechanisms and clinical applications
Neurotoxins generally inhibit or promote the release of neurotransmitters or bind to
receptors that are located in the pre-or post-synaptic membranes, thereby affecting …
receptors that are located in the pre-or post-synaptic membranes, thereby affecting …
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry
TT Talele - Journal of Medicinal Chemistry, 2017 - ACS Publications
The gem-dimethyl moiety is a structural feature frequently found in many natural products of
clinical interest, including, but not limited to, taxanes, epothilones, statins, retinoids, di …
clinical interest, including, but not limited to, taxanes, epothilones, statins, retinoids, di …
Pharmacological methods of pain management: Narrative review of medication used
NM Alorfi - International Journal of General Medicine, 2023 - Taylor & Francis
Background Pain management is a critical aspect of healthcare, aimed at alleviating
discomfort and improving the quality of life for individuals experiencing acute or chronic …
discomfort and improving the quality of life for individuals experiencing acute or chronic …
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain
MS Rahman, BS Winsvold, SOC Chavez… - Annals of the …, 2021 - ard.bmj.com
Background and objectives Chronic widespread musculoskeletal pain (CWP) is a symptom
of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable …
of fibromyalgia and a complex trait with poorly understood pathogenesis. CWP is heritable …
Thalamocortical circuits drive remifentanil-induced postoperative hyperalgesia
Y Jin, Y Mao, D Chen, Y Tai, R Hu… - The Journal of …, 2022 - Am Soc Clin Investig
Remifentanil-induced hyperalgesia (RIH) is a severe but common postoperative clinical
problem with elusive underlying neural mechanisms. Here, we discovered that …
problem with elusive underlying neural mechanisms. Here, we discovered that …
Mirogabalin: first global approval
ED Deeks - Drugs, 2019 - Springer
Mirogabalin besylate (hereafter mirogabalin)[Tarlige®] is an orally administered
gabapentinoid developed by Daiichi Sankyo for the treatment of peripheral neuropathic pain …
gabapentinoid developed by Daiichi Sankyo for the treatment of peripheral neuropathic pain …
Pharmacological inhibition of voltage-gated Ca2+ channels for chronic pain relief
S Lee - Current neuropharmacology, 2013 - ingentaconnect.com
Chronic pain is a major therapeutic problem as the current treatment options are
unsatisfactory with low efficacy and deleterious side effects. Voltage-gated Ca2+ channels …
unsatisfactory with low efficacy and deleterious side effects. Voltage-gated Ca2+ channels …