Radionuclide imaging technologies and their use in evaluating asthma drug deposition in the lungs

SP Newman, GR Pitcairn, PH Hirst, L Rankin - Advanced drug delivery …, 2003 - Elsevier
Whole lung and regional lung deposition of inhaled asthma drugs in the lungs can be
quantified using either two-dimensional or three-dimensional radionuclide imaging …

Inhaled GM-CSF for pulmonary alveolar proteinosis

R Tazawa, T Ueda, M Abe, K Tatsumi… - … England Journal of …, 2019 - Mass Medical Soc
Background Pulmonary alveolar proteinosis is a disease characterized by abnormal
accumulation of surfactant in the alveoli. Most cases are autoimmune and are associated …

Inhaled granulocyte/macrophage–colony stimulating factor as therapy for pulmonary alveolar proteinosis

R Tazawa, BC Trapnell, Y Inoue, T Arai… - American journal of …, 2010 - atsjournals.org
Rationale: Inhaled granulocyte/macrophage–colony stimulating factor (GM-CSF) is a
promising therapy for pulmonary alveolar proteinosis (PAP) but has not been adequately …

[图书][B] Pharmaceutical inhalation aerosol technology

AJ Hickey - 2003 - taylorfrancis.com
This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

The Rationale and Evidence for Use of Inhaled Antibiotics to Control Pseudomonas aeruginosa Infection in Non-cystic Fibrosis Bronchiectasis

R Dhand - Journal of aerosol medicine and pulmonary drug …, 2018 - liebertpub.com
Non-cystic fibrosis bronchiectasis (NCFBE) is a chronic inflammatory lung disease
characterized by irreversible dilation of the bronchi, symptoms of persistent cough and …

Pharmaceutical aerosol composition

J Jauernig, FC Lintz, M Keller, I Friedrich - US Patent 7,758,886, 2010 - Google Patents
Sterile compositions for administration as aerosols are described. They contain an active
agent which is poorly water-soluble, a non-ionic surfactant acomponent and a phos pholipid …

Standardization of techniques for using planar (2D) imaging for aerosol deposition assessment of orally inhaled products

S Newman, WD Bennett, M Biddiscombe… - Journal of aerosol …, 2012 - liebertpub.com
Two-dimensional (2D or planar) imaging with 99mTc radiolabels enables quantification of
whole-lung and regional lung depositions for orally inhaled drug products. This article …

Successful respiratory immunization with dry powder live-attenuated measles virus vaccine in rhesus macaques

WH Lin, DE Griffin, PA Rota… - Proceedings of the …, 2011 - National Acad Sciences
Measles remains an important cause of childhood mortality worldwide. Sustained high
vaccination coverage is the key to preventing measles deaths. Because measles vaccine is …

Improvement of alveolar glutathione and lung function but not oxidative state in cystic fibrosis

M Griese, J Ramakers, A Krasselt… - American journal of …, 2004 - atsjournals.org
Chronic neutrophilic inflammation leads to oxidative damage, which may play an important
role in the pathogenesis of cystic fibrosis lung disease. Bronchoalveolar lavage levels of the …

Comparison of breath-enhanced to breath-actuated nebulizers for rate, consistency, and efficiency

K Leung, E Louca, AL Coates - Chest, 2004 - Elsevier
Objectives: To evaluate differences between three new-generation nebulizers—Pari LC Star
(Pari Respiratory Equipment; Mississauga, ON, Canada), AeroEclipse (Trudell Medical …