Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Dopamine: functions, signaling, and association with neurological diseases

MO Klein, DS Battagello, AR Cardoso… - Cellular and molecular …, 2019 - Springer
The dopaminergic system plays important roles in neuromodulation, such as motor control,
motivation, reward, cognitive function, maternal, and reproductive behaviors. Dopamine is a …

Enhanced uptake of BPA in the presence of nanoplastics can lead to neurotoxic effects in adult zebrafish

Q Chen, D Yin, Y Jia, S Schiwy, J Legradi… - Science of the Total …, 2017 - Elsevier
Plastic particles have been proven to be abundant in the aquatic environment, raising
concerns about their potential toxic effects. In the present study, we determined the …

The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue

R Brisch, A Saniotis, R Wolf, H Bielau… - Frontiers in …, 2014 - frontiersin.org
Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia. The
revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and …

The physiology, signaling, and pharmacology of dopamine receptors

JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Monoaminergic neuropathology in Alzheimer's disease

G Šimić, MB Leko, S Wray, CR Harrington… - Progress in …, 2017 - Elsevier
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

[HTML][HTML] Focus: The Aging Brain: Side effects of a dopamine agonist therapy for Parkinson's disease: A mini-review of clinical pharmacology

JA Borovac - The Yale journal of biology and medicine, 2016 - ncbi.nlm.nih.gov
Dopamine agonists (DA) are therapeutic agents that are commonly used in the treatment of
Parkinson's disease (PD). They can reduce undesired motor fluctuations and delay the …

Regulation and function of selenoproteins in human disease

FP Bellinger, AV Raman, MA Reeves… - Biochemical …, 2009 - portlandpress.com
Selenoproteins are proteins containing selenium in the form of the 21st amino acid,
selenocysteine. Members of this protein family have many diverse functions, but their …

Bioconcentration and transfer of the organophorous flame retardant 1, 3-dichloro-2-propyl phosphate causes thyroid endocrine disruption and developmental …

Q Wang, NLS Lai, X Wang, Y Guo… - … science & technology, 2015 - ACS Publications
Organophosphate flame retardants are emerging environmental contaminants, although
knowledge of their health risks is limited. Here, thyroid hormone homeostasis and neuronal …

Removing obstacles in neuroscience drug discovery: the future path for animal models

A Markou, C Chiamulera, MA Geyer… - …, 2009 - nature.com
Despite great advances in basic neuroscience knowledge, the improved understanding of
brain functioning has not yet led to the introduction of truly novel pharmacological …