Although more than 100 drugs have been examined clinically, tissue plasminogen activator
remains the only drug approved for the treatment of acute ischemic stroke. Since the …

Stroke commonly leads to adult disability and death worldwide. Its major symptoms are
spastic hemiplegia and discordant motion, consequent to neuronal cell death induced by …

Protocatechuic acid (PCA) has been well studied for its neuroprotection value in several
diseases, but the effect in intracerebral haemorrhage (ICH) has not been reported. Here we …

17β‐Oestradiol (E2) is an important hormone signal that regulates multiple tissues and
functions in the body. This review focuses on the neuroprotective actions of E2 in the brain …

Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

We have previously reported that a single injection of an ultra-low dose of delta-9-
tetrahydrocannabinol (THC; the psychoactive ingredient of marijuana) protected the brain …

Exposure to cigarette smoke has been implicated in the progression of cerebrovascular and
neurological disorders like stroke through inflammation and blood-brain barrier disruption. In …

As the knowledge on the estrogenic system in the brain grows, the possibilities to modulate
it in order to afford further neuroprotection in brain damaging disorders so do it. We have …

Brain edema forms rapidly in the early hours of ischemic stroke by increased secretion of
Na, Cl, and water into the brain across an intact blood-brain barrier (BBB), together with …

Background. EA therapy is a traditional therapeutic approach for alleviation of cerebral I/R‐
induced brain injury. We investigated the effect of EA on MCAO rat model to examine the …