[HTML][HTML] A Consensus Statement on acromegaly therapeutic outcomes

S Melmed, MD Bronstein, P Chanson… - Nature Reviews …, 2018 - nature.com
Abstract The 11th Acromegaly Consensus Conference in April 2017 was convened to
update recommendations on therapeutic outcomes for patients with acromegaly. Consensus …

Systemic complications of acromegaly and the impact of the current treatment landscape: an update

MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

[HTML][HTML] Somatostatin receptor ligands and resistance to treatment in pituitary adenomas

D Cuevas-Ramos, M Fleseriu - Journal of molecular …, 2014 - jme.bioscientifica.com
Somatostatin (SST), an inhibitory polypeptide with two biologically active forms SST14 and
SST28, inhibits GH, prolactin (PRL), TSH, and ACTH secretion in the anterior pituitary gland …

Treatment of clinically nonfunctioning pituitary adenomas with dopamine agonists

Y Greenman, O Cooper, I Yaish… - European Journal of …, 2016 - academic.oup.com
Objective Clinically nonfunctioning pituitary adenoma (NFPA) remains the only pituitary
tumor subtype for which no effective medical therapy is available or recommended. We …

Novel pathway for somatostatin analogs in patients with acromegaly

MR Gadelha, L Kasuki, M Korbonits - Trends in Endocrinology & …, 2013 - cell.com
Acromegaly is a chronic disease with increased morbidity and mortality, where usually
multiple treatment modalities are used. The somatostatin analogs (SSAs) are the mainstay of …

Management of endocrine disease: personalized medicine in the treatment of acromegaly

L Kasuki, LE Wildemberg… - European Journal of …, 2018 - academic.oup.com
Acromegaly is associated with high morbidity and elevated mortality when not adequately
treated. Surgery is the first-line treatment for most patients as it is the only one that can lead …

[HTML][HTML] Histopathological classification of non-functioning pituitary neuroendocrine tumors

E Manojlovic-Gacic, BE Engström, O Casar-Borota - Pituitary, 2018 - Springer
Non-functioning pituitary neuroendocrine tumors do not cause endocrine symptoms related
to hypersecretion of adenohypophyseal hormones and are clinically characterized by …

[HTML][HTML] Somatostatin and Somatostatin Receptors in Tumour Biology

U Kumar - International Journal of Molecular Sciences, 2023 - mdpi.com
Somatostatin (SST), a growth hormone inhibitory peptide, is expressed in endocrine and
non-endocrine tissues, immune cells and the central nervous system (CNS). Post-release …

Update on the clinicopathology of pituitary adenomas

CT Lim, MK Korbonits - Endocrine Practice, 2018 - Elsevier
Objective: Pituitary adenomas are the third most common central nervous system tumors
and arise from the anterior pituitary within the pituitary fossa. Methods: Literature review and …

Magnetic resonance imaging as a predictor of response to somatostatin analogs in acromegaly after surgical failure

M Puig-Domingo, E Resmini… - The Journal of …, 2010 - academic.oup.com
Context: Transsphenoidal surgery is considered first-line therapy for acromegaly; however,
there is often a need for adjunctive therapy. Somatostatin analogs (SSA) have greatly …