New insights into the molecular mechanism of intestinal fatty acid absorption

TY Wang, M Liu, P Portincasa… - European journal of …, 2013 - Wiley Online Library
Background Dietary fat is one of the most important energy sources of all the nutrients. Fatty
acids, stored as triacylglycerols (also called triglycerides) in the body, are an important …

Lipid metabolic enzymes: emerging drug targets for the treatment of obesity

Y Shi, P Burn - Nature reviews Drug discovery, 2004 - nature.com
Obesity is a complex disease that is regulated by both central and peripheral mechanisms.
New medicines for the treatment and prevention of obesity will need to overcome the …

New insights into the molecular actions of plant sterols and stanols in cholesterol metabolism

L Calpe-Berdiel, JC Escolà-Gil, F Blanco-Vaca - Atherosclerosis, 2009 - Elsevier
Plant sterols and stanols (phytosterols/phytostanols) are known to reduce serum low-density
lipoprotein (LDL)-cholesterol level, and food products containing these plant compounds are …

Regulation of intestinal cholesterol absorption

DQH Wang - Annu. Rev. Physiol., 2007 - annualreviews.org
The identification of defective structures in the ATP-binding cassette (ABC) transporters
ABCG5 and ABCG8 in patients with sitosterolemia suggests that these two proteins are an …

Other relevant components of nuts: phytosterols, folate and minerals

R Segura, C Javierre, MA Lizarraga… - British Journal of Nutrition, 2006 - cambridge.org
Nuts contain significant amounts of essential micronutrients that are associated with an
improved health status when consumed at doses beyond those necessary to prevent …

Sterol absorption by the small intestine

SD Turley, JM Dietschy - Current opinion in lipidology, 2003 - journals.lww.com
Intestinal cholesterol absorption represents a major route for the entry of cholesterol into the
body's miscible pools and therefore can potentially impact the plasma LDL-cholesterol …

Prevention of cholesterol gallstones by inhibiting hepatic biosynthesis and intestinal absorption of cholesterol

HH Wang, P Portincasa, O de Bari… - European journal of …, 2013 - Wiley Online Library
Background Cholesterol cholelithiasis is a multifactorial disease influenced by a complex
interaction of genetic and environmental factors and represents a failure of biliary …

New insights into the genetic regulation of intestinal cholesterol absorption

F Lammert, DQH Wang - Gastroenterology, 2005 - Elsevier
The small intestine is a unique organ providing dietary and reabsorbed biliary cholesterol to
the body. However, the molecular mechanisms whereby cholesterol is absorbed have not …

[HTML][HTML] Colesterol: Función biológica e implicaciones médicas

O Maldonado Saavedra, I Ramírez Sánchez… - Revista mexicana de …, 2012 - scielo.org.mx
Nuestro organismo sintetiza su propio colesterol, un porcentaje extra es obtenido de la
dieta. El colesterol forma parte de las membranas de nuestras células, sirve como precursor …

Perspectives in cholesterol-lowering therapy: the role of ezetimibe, a new selective inhibitor of intestinal cholesterol absorption

E Bruckert, P Giral, P Tellier - Circulation, 2003 - Am Heart Assoc
3124 survey of risk factor management with established CHD revealed that only half of those
patients receiving lipidlowering therapy had attained recommended lipid treatment goals. 3 …