[HTML][HTML] Customizing delivery nano-vehicles for precise brain tumor therapy

YB Miao, W Zhao, G Renchi, Y Gong, Y Shi - Journal of …, 2023 - Springer
Although some tumor has become a curable disease for many patients, involvement of the
central nervous system (CNS) is still a major concern. The blood–brain barrier (BBB), a …

Transferrin receptor 1 targeted nanomedicine for brain tumor therapy

J Li, Z Zhang, B Zhang, X Yan, K Fan - Biomaterials Science, 2023 - pubs.rsc.org
Achieving effective drug delivery to traverse the blood–brain barrier (BBB) and target tumor
cells remains the greatest challenge for brain tumor therapy. Importantly, the overexpressed …

Recent advances in intranasal administration for brain-targeting delivery: a comprehensive review of lipid-based nanoparticles and stimuli-responsive gel formulations

J Koo, C Lim, KT Oh - International Journal of Nanomedicine, 2024 - Taylor & Francis
Addressing disorders related to the central nervous system (CNS) remains a complex
challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry …

[HTML][HTML] Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo …

M Bakhtiyari-Ramezani, M Nohekhan, ME Akbari… - Scientific Reports, 2024 - nature.com
Recent research has highlighted the promising potential of cold atmospheric plasma (CAP)
in cancer therapy. However, variations in study outcomes are attributed to differences in …

[HTML][HTML] Photodynamic opening of the blood–brain barrier and the meningeal lymphatic system: the new niche in immunotherapy for brain tumors

O Semyachkina-Glushkovskaya, A Terskov… - Pharmaceutics, 2022 - mdpi.com
Photodynamic therapy (PDT) is a promising add-on therapy to the current standard of care
for patients with glioblastoma (GBM). The traditional explanation of the anti-cancer PDT …

Advances in antibody-based drugs and their delivery through the blood-brain barrier for targeted therapy and immunotherapy of gliomas

X Huang, S Shi, H Wang, T Zhao, Y Wang… - International …, 2023 - Elsevier
Gliomas are highly invasive and are the most common type of primary malignant brain
tumor. The routine treatments for glioma include surgical resection, radiotherapy, and …

Angiopep-2-Functionalized Lipid Cubosomes for Blood–Brain Barrier Crossing and Glioblastoma Treatment

X Cai, A Refaat, PY Gan, B Fan, H Yu… - … Applied Materials & …, 2024 - ACS Publications
Glioblastoma multiforme (GBM) is an aggressive brain cancer with high malignancy and
resistance to conventional treatments, resulting in a bleak prognosis. Nanoparticles offer a …

[HTML][HTML] Transferrin-targeted liposomes in glioblastoma therapy: a review

P Kawak, NMA Sawaftah, WG Pitt… - International Journal of …, 2023 - mdpi.com
Glioblastoma (GBM) is a highly aggressive brain tumor, and its treatment is further
complicated by the high selectivity of the blood–brain barrier (BBB). The scientific community …

[HTML][HTML] Genetically encoded self-assembling protein nanoparticles for the targeted delivery in vitro and in vivo

AS Obozina, EN Komedchikova, OA Kolesnikova… - Pharmaceutics, 2023 - mdpi.com
Targeted nanoparticles of different origins are considered as new-generation diagnostic and
therapeutic tools. However, there are no targeted drug formulations within the composition of …

Progress and Challenges in the Diagnosis and Treatment of Brain Cancer Using Nanotechnology

Y Ale, N Nainwal - Molecular Pharmaceutics, 2023 - ACS Publications
Primary brain cancer or brain cancer is the overgrowth of abnormal or malignant cells in the
brain or its nearby tissues that form unwanted masses called brain tumors. People with …