Image-based profiling is a maturing strategy by which the rich information present in
biological images is reduced to a multidimensional profile, a collection of extracted image …

The need for assembled existing and new toxicity data has accelerated as the amount of
chemicals introduced into commerce continues to grow and regulatory mandates require …

Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …

The predominantly animal-centric approach of chemical safety assessment has increasingly
come under pressure. Society is questioning overall performance, sustainability, continued …

Abstract Next-Generation Risk Assessment is defined as an exposure-led, hypothesis-driven
risk assessment approach that integrates new approach methodologies (NAMs) to assure …

Chemical risk assessments follow a long-standing paradigm that integrates hazard, dose–
response, and exposure information to facilitate quantitative risk characterization. Targeted …

Toxicity testing and regulation of advanced materials at the nanoscale, ie nanosafety, is
challenged by the growing number of nanomaterials and their property variants requiring …

The first edition of Bioanalytical Tools in Water Quality Assessment was released in 2012.
The field has exploded since and the second edition updates and reviews the application of …

During the past few decades, the science of toxicology has been undergoing a
transformation from observational to predictive science. New approach methodologies …

This paper presents a 10-step read-across (RAX) framework for use in cases where a
threshold of toxicological concern (TTC) approach to cosmetics safety assessment is not …