Management of frailty: opportunities, challenges, and future directions

E Dent, FC Martin, H Bergman, J Woo… - The Lancet, 2019 - thelancet.com
Frailty is a complex age-related clinical condition characterised by a decline in physiological
capacity across several organ systems, with a resultant increased susceptibility to stressors …

Frailty syndrome: implications and challenges for health care policy

G Kojima, AEM Liljas, S Iliffe - Risk management and healthcare …, 2019 - Taylor & Francis
Older adults are a highly heterogeneous group with variable health and functional life
courses. Frailty has received increasing scientific attention as a potential explanation of the …

[HTML][HTML] Physical frailty: ICFSR international clinical practice guidelines for identification and management

E Dent, JE Morley, AJ Cruz-Jentoft… - The Journal of nutrition …, 2019 - Elsevier
Objective The task force of the International Conference of Frailty and Sarcopenia Research
(ICFSR) developed these clinical practice guidelines to overview the current evidence-base …

[HTML][HTML] International clinical practice guidelines for sarcopenia (ICFSR): screening, diagnosis and management

E Dent, JE Morley, AJ Cruz-Jentoft, H Arai… - The Journal of nutrition …, 2018 - Elsevier
Objectives Sarcopenia, defined as an age-associated loss of skeletal muscle function and
muscle mass, occurs in approximately 6-22% of older adults. This paper presents evidence …

COVID‐19 and older people in Asia: Asian Working Group for Sarcopenia calls to action

WS Lim, CK Liang, P Assantachai… - Geriatrics & …, 2020 - Wiley Online Library
The coronavirus disease 2019 (COVID‐19) pandemic has casted a huge impact on global
public health and the economy. In this challenging situation, older people are vulnerable to …

Mild cognitive impairment in clinical practice: a review article

S Jongsiriyanyong… - American Journal of …, 2018 - journals.sagepub.com
The spectrum of cognitive decline in the elderly ranges from what can be classified as
normal cognitive decline with aging to subjective cognitive impairment to mild cognitive …

Different cognitive frailty models and health-and cognitive-related outcomes in older age: from epidemiology to prevention

F Panza, M Lozupone, V Solfrizzi… - Journal of …, 2018 - content.iospress.com
Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …

[HTML][HTML] Malnutrition screening and assessment in hospitalised older people: a review

E Dent, EO Hoogendijk, R Visvanathan… - The Journal of nutrition …, 2019 - Elsevier
Malnutrition (undernutrition) remains one of the most serious health problems for older
people worldwide. Many factors contribute to malnutrition in older people, including: loss of …

Comparative effectiveness of non-pharmacological interventions for frailty: a systematic review and network meta-analysis

X Sun, W Liu, Y Gao, L Qin, H Feng, H Tan… - Age and …, 2023 - academic.oup.com
Background Frailty endangers the health of older adults. Furthermore, the prevalence of
frailty continues to increase as the global population ageing. Objective To update evidence …

Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty

OJ Luo, W Lei, G Zhu, Z Ren, Y Xu, C Xiao, H Zhang… - Nature Aging, 2022 - nature.com
Frailty is an intermediate status of the human aging process, associated with
decompensated homeostasis and death. The immune phenotype of frailty and its underlying …