Deep brain stimulation for obsessive-compulsive disorder and depression

SA Sheth, HS Mayberg - Annual Review of Neuroscience, 2023 - annualreviews.org
The field of stereotactic neurosurgery developed more than 70 years ago to address a
therapy gap for patients with severe psychiatric disorders. In the decades since, it has …

Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?

H Wu, M Hariz, V Visser-Vandewalle, L Zrinzo… - Molecular …, 2021 - nature.com
A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-
refractory obsessive-compulsive disorder (OCD) can be considered an established therapy …

Amygdala and hypothalamus: historical overview with focus on aggression

FV Gouveia, C Hamani, ET Fonoff, H Brentani… - …, 2019 - journals.lww.com
Aggressiveness has a high prevalence in psychiatric patients and is a major health problem.
Two brain areas involved in the neural network of aggressive behavior are the amygdala …

The psychopharmacology of obsessive-compulsive disorder: a preclinical roadmap

H Szechtman, BH Harvey, EZ Woody… - Pharmacological reviews, 2020 - ASPET
This review evaluates current knowledge about obsessive-compulsive disorder (OCD), with
the goal of providing a roadmap for future directions in research on the …

The re-emergence of psychiatric neurosurgery: insights from a cross-national study of newspaper and magazine coverage

LY Cabrera, M Bittlinger, H Lou, S Müller, J Illes - Acta neurochirurgica, 2018 - Springer
Background Surgical approaches to treat psychiatric disorders have made a comeback.
News media plays an essential role in exposing the public to trends in health care such as …

Acute effects of electrical stimulation of the bed nucleus of the stria terminalis/internal capsule in obsessive-compulsive disorder

L Winter, I Heitland, A Saryyeva, G Lütjens… - World Neurosurgery, 2018 - Elsevier
Background Deep brain stimulation (DBS) has been introduced as a treatment option for
treatment-resistant obsessive-compulsive disorder (OCD). However, the optimal stimulation …

Corpus callosum area and sectioning: a radioanatomical study correlated with MRI and cadaver morphometry

YE Guner, A Comert, A Aslan, Y Gungor - Surgical and Radiologic …, 2023 - Springer
Purpose The corpus callosum (CC) is the primary interhemispheric connection between the
two cerebral hemispheres. Besides their similar morphological characters, there are …

Pathophysiology of obsessive-compulsive disorder: insights from normal function and neurotoxic effects of drugs, infection, and brain injury

H Szechtman, S Shivji, EZ Woody - Handbook of Neurotoxicity, 2023 - Springer
Clinical presentation of obsessive-compulsive disorder (OCD) is summarized, and a
theoretical model of the disorder and its neurobiology are described. The model is used to …

Neuroplasticity and the brain connectome: what can Jean Talairach's reflections bring to modern psychosurgery?

P Bourdillon, C Apra, M Lévêque, F Vinckier - Neurosurgical Focus, 2017 - thejns.org
Contrary to common psychosurgical practice in the 1950s, Dr. Jean Talairach had the
intuition, based on clinical experience, that the brain connectome and neuroplasticity had a …

Frontal lobotomy

RW Byard - Forensic Science, Medicine, and Pathology, 2017 - Springer
The use of surgical techniques to treat psychological conditions, so-called psychosurgery,
has been a feature of therapeutic interventions in many societies since Neolithic times, with …