The human malaria parasite Plasmodium falciparum undergoes a complex life cycle in two
hosts, mammalian and mosquito, where it is constantly subjected to environmental changes …

The development of novel anti‐infectives requires unprecedented strategies targeting
pathways which are solely present in pathogens but absent in humans. Following this …

Citrate synthase catalyzes the first and the rate-limiting reaction of the tricarboxylic acid
(TCA) cycle, producing citrate from the condensation of oxaloacetate and acetyl-coenzyme …

Abstract Die Entwicklung neuer Antiinfektiva erfordert innovative Strategien zur gezielten
Ausnutzung von Stoffwechselwegen in Krankheitserregern, die in menschlichen Zellen …