[HTML][HTML] A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa

L Ndwiga, KM Kimenyi, K Wamae, V Osoti… - International Journal for …, 2021 - Elsevier
Artemisinin resistance (AR) emerged in South East Asia 13 years ago and the identification
of the resistance conferring molecular marker, Plasmodium falciparum Kelch 13 (Pfk13), 7 …

Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review

NK Kayiba, DM Yobi… - The Lancet Infectious …, 2021 - thelancet.com
The spread of Plasmodium falciparum isolates carrying mutations in the kelch13 (Pfkelch13)
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …

[HTML][HTML] Potential opportunities and challenges of deploying next generation sequencing and CRISPR-Cas systems to support diagnostics and surveillance towards …

BM Lyimo, ZR Popkin-Hall, DJ Giesbrecht… - Frontiers in Cellular …, 2022 - frontiersin.org
Recent developments in molecular biology and genomics have revolutionized biology and
medicine mainly in the developed world. The application of next generation sequencing …

Past and current biological factors affecting malaria in the low transmission setting of Botswana: A review

ZA Bango, L Tawe, CW Muthoga… - Infection, Genetics and …, 2020 - Elsevier
Malaria continues to be one of the top infectious agents contributing to morbidity and
mortality in sub-Saharan Africa. Annually, Botswana accounts only for a small proportion of …

Targeted deep amplicon sequencing of kelch 13 and cytochrome b in Plasmodium falciparum isolates from an endemic African country using the Malaria …

M L'Episcopia, J Kelley, D Patel, S Schmedes… - Parasites & vectors, 2020 - Springer
Background Routine molecular surveillance for imported drug-resistant malaria parasites to
the USA and European Union is an important public health activity. The obtained molecular …

Similar Ferroportin Q248H polymorphism prevalence in patients with Plasmodium falciparum malaria and control subjects in the low-endemic setting of Botswana

MG Manake, P Ramatlho, TD Ntereke, L Tawe… - Clinica Chimica …, 2021 - Elsevier
Introduction Recent evidence suggests that ferroportin (FPN) Q248H may confer a survival
advantage against malaria by reducing erythrocytic intracellular iron in Africans. We …

[PDF][PDF] Mise en place d'un système de surveillance moléculaire de la résistance aux antipaludiques en République Démocratique du Congo: Rôle, Avantages et Défis

NK KALENDA - 2021 - dial.uclouvain.be
La pharmaco-résistance est un obstacle majeur au contrôle du paludisme en RDC. Deux
revues systématiques et trois études originales indiquent une résistance répandue du P …