Almost 60 years have passed since the initial discovery by Hubel and Wiesel that changes
in neuronal activity can elicit developmental rewiring of the central nervous system (CNS) …

The authors examine US-based evidence that connects characteristics of the social
environment with outcomes across the psychosis continuum, from psychotic experiences to …

Since living in cities is associated with an increased risk for mental disorders such as anxiety
disorders, depression, and schizophrenia, it is essential to understand how exposure to …

Decades of research have revealed numerous risk factors for mental disorders beyond
genetics, but their consistency and magnitude remain uncertain. We conducted a “meta …

Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …

Available treatment methods have shown little effect on the burden associated with mental
health disorders. We review promising universal, selective, and indicated preventive mental …

Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and
protective factors have been suggested. This umbrella review aimed to classify the strength …

Background Twin studies have provided evidence that both genetic and environmental
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …

Background More than half of the global population currently lives in cities, with an
increasing trend for further urbanization. Living in cities is associated with increased …

Objective To provide a comprehensive analysis of cytokine perturbations in antipsychotic
naïve firstepisode psychosis (FEP) populations and assess the relationship between …