Background Biomarker changes that occur in the period between normal cognition and the
diagnosis of sporadic Alzheimer's disease have not been extensively investigated in …

Alzheimer's disease (AD) is a pressing global issue, demanding effective diagnostic
approaches. This systematic review surveys the recent literature (2018 onwards) to …

Dementia management has evolved with drugs such as lecanemab, shifting management
from palliative care to early diagnosis and intervention. However, the administration of these …

Introduction Alzheimer's disease (AD), a major cause of dementia globally, imposes
significant societal and personal costs. This review explores the efficacy of physical exercise …

In China, the aging population and the increasing incidence of Alzheimer's disease (AD)
and other dementias have emerged as major medical concerns. Extensive research and …

To understand how aging affects functional decline and increases disease risk, it is
necessary to develop accurate and reliable measures of how fast a person is aging …

BACKGROUND Mild cognitive impairment (MCI) heightens Alzheimer's disease (AD) risk,
with diabetes mellitus (DM) potentially exacerbating this vulnerability. This study identifies …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) Clinical Core is
responsible for coordination of all clinical activities at the ADNI sites, including project …

Generative AI models have recently achieved mainstream attention with the advent of
powerful approaches such as stable diffusion, DALL-E and MidJourney. The underlying …

The Tau protein plays a pivotal role in the organization and reinforcement of microtubules,
which are essential for the normal functioning of neurons and the brain. Under diseased …