Toll-like Receptor 10 in Helicobacter pylori Infection

H Nagashima, S Iwatani, M Cruz… - The Journal of …, 2015 - academic.oup.com
Innate immunity plays important roles in the primary defense against pathogens, and
epidemiological studies have suggested a role for Toll-like receptor 1 (TLR1) in Helicobacter …

Helicobacter pylori and gastric cancer

DM Pritchard, JE Crabtree - Current opinion in gastroenterology, 2006 - journals.lww.com
Complex interactions between several bacterial, host genetic and environmental factors
determine whether H. pylori infected individuals develop gastric carcinoma. The importance …

T cell cytokines impact epithelial cell responses during Helicobacter pylori infection

HMS Algood - The Journal of Immunology, 2020 - journals.aai.org
The goal of this Brief Review is to highlight literature that demonstrates how cytokines made
by T lymphocytes impact the gastric epithelium, especially during Helicobacter pylori …

Anti‐inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor‐κB inhibitor, on Helicobacter pylori‐induced gastritis in Mongolian gerbils

T Toyoda, T Tsukamoto, S Takasu, L Shi… - … journal of cancer, 2009 - Wiley Online Library
Nuclear factor‐κB (NF‐κB) plays a major role in host inflammatory responses and
carcinogenesis and as such is an important drug target for adjuvant therapy. In this study, we …

Anti‐Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori‐Induced Chronic Gastritis in Mongolian Gerbils

T Toyoda, L Shi, S Takasu, YM Cho, Y Kiriyama… - …, 2016 - Wiley Online Library
Background Spices have been used for thousands of years, and recent studies suggest that
certain spices confer beneficial effects on gastric disorders. The purpose of this study was to …

Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori

N Yoshizawa, Y Takenaka, H Yamaguchi… - Laboratory …, 2007 - nature.com
Abstract Spasmolytic polypeptide (TFF2)-expressing metaplasia (SPEM) is observed in
mucosa adjacent to human gastric cancer and in fundic glands showing oxyntic atrophy in …

Association between virulence factors of helicobacter pylori and gastric mucosal interleukin-18 mRNA expression in dyspeptic patients

N Bagheri, A Taghikhani, G Rahimian… - Microbial …, 2013 - Elsevier
Abstract Background Helicobacter pylori (Hp) infection is associated with gastritis and
marked infiltration of the gastric mucosa by several cytokines secreting inflammatory cells …

Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation

K Hur, T Niwa, T Toyoda, T Tsukamoto… - …, 2011 - academic.oup.com
Chronic inflammation is deeply involved in induction of aberrant DNA methylation, but it is
unclear whether any type of persistent inflammation can induce methylation and how …

Virulence factors of Helicobacter pylori vacA increase markedly gastric mucosal TGF-β1 mRNA expression in gastritis patients

G Rahimian, MH Sanei, H Shirzad… - Microbial …, 2014 - Elsevier
Objective Helicobacter pylori (H. pylori) infection is the main cause of gastric inflammation.
Regulatory T cells (Treg cells) suppress the activation and proliferation of antigen-specific T …

4‐Vinyl‐2,6‐dimethoxyphenol (canolol) suppresses oxidative stress and gastric carcinogenesis in Helicobacter pylori‐infected carcinogen‐treated Mongolian gerbils

X Cao, T Tsukamoto, T Seki, H Tanaka… - … journal of cancer, 2008 - Wiley Online Library
Oxidative stress is linked to gastric carcinogenesis because of its ability to damage DNA.
Here we examined antioxidative and anti‐inflammatory effects of 4‐vinyl‐2, 6 …