The updated role of exosomal proteins in the diagnosis, prognosis, and treatment of cancer

X Wang, J Huang, W Chen, G Li, Z Li… - Experimental & molecular …, 2022 - nature.com
Exosomes are vesicles encompassed by a lipid bilayer that are released by various living
cells. Exosomal proteins are encapsulated within the membrane or embedded on the …

Heat shock proteins and HSF1 in cancer

AM Cyran, A Zhitkovich - Frontiers in oncology, 2022 - frontiersin.org
Fitness of cells is dependent on protein homeostasis which is maintained by cooperative
activities of protein chaperones and proteolytic machinery. Upon encountering protein …

[HTML][HTML] Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment

S Yang, H Xiao, L Cao - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Heat shock proteins (HSPs) are a group of proteins, also known as molecular chaperones,
which participate in protein folding and maturation in response to stresses or high …

[HTML][HTML] Extracellular heat shock proteins and cancer: New perspectives

Z Albakova, MKS Siam, PK Sacitharan… - Translational …, 2021 - Elsevier
Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …

Acetyltransferase from Akkermansia muciniphila blunts colorectal tumourigenesis by reprogramming tumour microenvironment

Y Jiang, Y Xu, C Zheng, L Ye, P Jiang, S Malik, G Xu… - Gut, 2023 - gut.bmj.com
Objective The protein post-translational modification (PTM) in host cells can be rewritten by
bacterial enzymes and represents an unprecedented mechanism in the communication …

Potentiality of exosomal proteins as novel cancer biomarkers for liquid biopsy

C Hu, W Jiang, M Lv, S Fan, Y Lu, Q Wu… - Frontiers in …, 2022 - frontiersin.org
Liquid biopsy has been rapidly developed in recent years due to its advantages of non-
invasiveness and real-time sampling in cancer prognosis and diagnosis. Exosomes are …

HSP70 and HSP90 in cancer: cytosolic, endoplasmic reticulum and mitochondrial chaperones of tumorigenesis

Z Albakova, Y Mangasarova, A Albakov… - Frontiers in …, 2022 - frontiersin.org
HSP70 and HSP90 are two powerful chaperone machineries involved in survival and
proliferation of tumor cells. Residing in various cellular compartments, HSP70 and HSP90 …

Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets

R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
Regulated cell death (RCD) is a critical and active process that is controlled by specific
signal transduction pathways and can be regulated by genetic signals or drug interventions …

Biomarkers of radiotherapy-induced immunogenic cell death

RDW Vaes, LEL Hendriks, M Vooijs, D De Ruysscher - Cells, 2021 - mdpi.com
Radiation therapy (RT) can induce an immunogenic variant of regulated cell death that can
initiate clinically relevant tumor-targeting immune responses. Immunogenic cell death (ICD) …

Advances in exosomes‐based drug delivery systems

C Gutierrez‐Millan, C Calvo Díaz… - Macromolecular …, 2021 - Wiley Online Library
Exosomes, a subgroup of extracellular vesicles, are important mediators of long‐distance
intercellular communication and are involved in a diverse range of biological processes …