Objective: Idiopathic pulmonary fibrosis poses a significant therapeutic challenge because
of its progressive course. Since oxidative stress plays an important role in the pathogenesis …

Biofilms are a key factor in the development of both acute and chronic airway infections.
Their relevance is well established in ventilator associated pneumonia, one of the most …

The objective of this study was to explore the effects of antioxidant treatments, specifically N-
acetylcysteine (NAC) and N-acetylcysteine amide (NACA), in a mouse model of chlorine (Cl …

A simple, precise and accurate reversed-phase liquid chromatographic method has been
developed for the simultaneous estimation of ambroxol hydrochloride and azithromycin in …

The lungs are continually exposed to relatively-high O2 tensions, and as such, in
comparison with other organs, they represent a unique tissue for the damaging effects of …

The purpose of this study was to investigate the protective effects of ambroxol in psoriasis-
like skin inflammation both in vitro and in vivo and delineate the molecular mechanism of …

Paraquat (PQ) is a commonly used herbicide that induces oxidative stress via reactive
oxygen species (ROS) generation. This study aimed to investigate the effects of the …

Background: N-acetylcysteine (NAC) and ambroxol (AMB) have recently been proposed as
possible therapeutic agents in the treatment of pulmonary disorders. IL-12 plays an …

Introduction Myrtol standardized is established in the treatment of acute and chronic
bronchitis and sinusitis. It increases mucociliar clearance and has muco-secretolytic effects …

Idiopathic pulmonary fibrosis (IPF) is thought to involve inflammatory infiltration of
leukocytes, lung injury induced by reactive oxygen species (ROS), in particular superoxide …