Transforming the understanding of brain immunity

G Castellani, T Croese, JM Peralta Ramos, M Schwartz - Science, 2023 - science.org
Contemporary studies have completely changed the view of brain immunity from envisioning
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …

A comprehensive review of the health perspectives of resveratrol

A Rauf, M Imran, HAR Suleria, B Ahmad, DG Peters… - Food & function, 2017 - pubs.rsc.org
Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

[HTML][HTML] Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions …

Dietary polyphenols: A novel strategy to modulate microbiota-gut-brain axis

D Serra, LM Almeida, TCP Dinis - Trends in food science & technology, 2018 - Elsevier
Background Although great advances have been made in the discovery of new drugs that
effectively penetrate the brain and alleviate neurological disorders, such as Alzheimer's …

The BTBR mouse model of idiopathic autism–Current view on mechanisms

KZ Meyza, DC Blanchard - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental
disorder, with current estimates of more than 1% of affected children across nations. The …

Parental inflammatory bowel disease and autism in children

A Sadik, C Dardani, P Pagoni, A Havdahl… - Nature Medicine, 2022 - nature.com
Evidence linking parental inflammatory bowel disease (IBD) with autism in children is
inconclusive. We conducted four complementary studies to investigate associations …

The Probiotic Lactobacillus fermentum Prevents Dysbiosis and Vascular Oxidative Stress in Rats with Hypertension Induced by Chronic Nitric Oxide Blockade

I Robles‐Vera, M Toral… - Molecular nutrition & …, 2018 - Wiley Online Library
Scope Whether the probiotic Lactobacillus fermentum CECT5716 (LC40) ameliorates
hypertension in rats with chronic nitric oxide (NO) synthase inhibition is tested. Methods and …

The mechanisms of CHD8 in neurodevelopment and autism spectrum disorders

O Weissberg, E Elliott - Genes, 2021 - mdpi.com
Chromodomain-helicase-DNA-binding protein 8 (CHD8) has been identified as one of the
genes with the strongest association with autism. The CHD8 protein is a transcriptional …

Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in …

A Nadeem, SF Ahmad, NO Al-Harbi, SM Attia… - Behavioural brain …, 2019 - Elsevier
Autism is a neurodevelopmental disease which is characterized by its core behavioral
symptoms such as impairment in social interaction and stereotyped repetitive behavior …

Immunological dysfunction in autism spectrum disorder: a potential target for therapy

J Marchezan, EGA Winkler dos Santos… - …, 2019 - karger.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with an
unknown etiology and currently few effective therapies. Immune system alterations have …