Therapeutic potential of nutraceuticals to protect brain after stroke

B Chelluboina, R Vemuganti - Neurochemistry International, 2021 - Elsevier
Stroke leads to significant neuronal death and long-term neurological disability due to
synergistic pathogenic mechanisms. Stroke induces a change in eating habits and in many …

Regulation of gene expression through food—Curcumin as a sirtuin activity modulator

A Ungurianu, A Zanfirescu, D Margină - Plants, 2022 - mdpi.com
The sirtuin family comprises NAD+-dependent protein lysine deacylases, mammalian
sirtuins being either nuclear (SIRT1, SIRT2, SIRT6, and SIRT7), mitochondrial (SIRT3 …

Isolation and Identification of Human Gut Bacteria Capable of Converting Curcumin to Its Hydrogenated Metabolites

M Luo, S Wong, P Thanuphol, H Du… - Journal of Agricultural …, 2024 - ACS Publications
Curcumin is widely recognized for its health benefits, though the role of gut microbiota in its
metabolic transformation was not well studied. In this study, bacterial strains capable of …

Improvement of the Solubilization and Extraction of Curcumin in an Edible Ternary Solvent Mixture

V Huber, L Muller, J Hioe, P Degot, D Touraud, W Kunz - Molecules, 2021 - mdpi.com
A water-free, ternary solvent mixture consisting of a natural deep eutectic solvent (NADES),
ethanol, and triacetin was investigated concerning its ability to dissolve and extract curcumin …

Development of a rapid, sensitive, and selective LC–MS/MS method for quantifying curcumin levels in healthy human urine: Effect of pepper on curcumin …

S Khajeh pour, C Blanton, B Ghimire… - Food Science & …, 2023 - Wiley Online Library
Curcumin (CCM), a culinary spice, is widely consumed for its health benefits for managing
oxidative and inflammatory conditions, metabolic syndrome, arthritis, and hyperlipidemia …

Curcumin: a promising tool to develop preventive and therapeutic strategies against non-communicable diseases, still requiring verification by sound clinical trials

R Masella, F Cirulli - Nutrients, 2022 - mdpi.com
Curcumin is a pleiotropic compound found in the rhizome of Curcuma longa (turmeric).
Curcuma longa has been widely used as a spice for a long time, especially in Asian …

Curcumin in inflammatory bowel diseases: Cellular targets and molecular mechanisms

ASDP Martins, MDC Alves, ORP DE ARAÚJO… - Biocell, 2023 - Elsevier
Curcumin, a natural product, has exhibited promising effects in both animal models and
clinical trials, interacting with a multitude of factors linked to Inflammatory Bowel Disease …

Gut relief formula attenuates dextran sulfate sodium-induced colitis by regulating NF-κB signaling and the intestinal microbiota in mice

X Si, N Liu, H Jia, J Wang, L Pan, L Dong, Z Rong… - Food & Function, 2021 - pubs.rsc.org
Background. Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the
gastrointestinal tract. The nutrition care gut relief formula (GR), a combination of natural …

Multimodal strategies to fight obesity: research on tailored therapies based on natural and synthetic compounds for prevention, management and treatment

A D'Anneo, M Lauricella - International Journal of Molecular Sciences, 2023 - mdpi.com
In the past 50 years, the global prevalence of obesity and overweight has tripled, reaching
pandemic proportions and blatantly representing an urgent problem for public health [1, 2] …

Curcumin loading on alginate nano-micelle for anti-infection and colonic wound healing

Z Zhang, X Zhang - Journal of Biomedical Nanotechnology, 2021 - ingentaconnect.com
Despite the antibacterial, and anti-inflammatory properties of curcumin (C), its effect on
wound healing, especially in the colorectal, is ambiguous. Moreover, due to the hydrophobic …