The roles and regulation of the KLF5 transcription factor in cancers

Y Luo, C Chen - Cancer science, 2021 - Wiley Online Library
Krüppel‐like factor 5 (KLF5) is a member of the KLF family. Recent studies have suggested
that KLF5 regulates the expression of a large number of new target genes and participates …

Influence of olive oil and its components on breast cancer: Molecular mechanisms

R Moral, E Escrich - Molecules, 2022 - mdpi.com
Breast cancer is the most frequent malignant neoplasia and a leading cause of mortality in
women worldwide. The Mediterranean diet has been proposed as a healthy dietary pattern …

Recent Advancement in Breast Cancer Research: Insights from Model Organisms—Mouse Models to Zebrafish

SS Singhal, R Garg, A Mohanty, P Garg, SK Ramisetty… - Cancers, 2023 - mdpi.com
Simple Summary The current article provides an overview of the significance of using
various mouse and zebrafish models in cancer research. In addition, this review discusses …

Cholesterol-modified sphingomyelin chimeric lipid bilayer for improved therapeutic delivery

Z Wang, W Li, Y Jiang, J Park, KM Gonzalez… - Nature …, 2024 - nature.com
Cholesterol (Chol) fortifies packing and reduces fluidity and permeability of the lipid bilayer
in vesicles (liposomes)-mediated drug delivery. However, under the physiological …

Experimental mouse models for translational human cancer research

Y Zhou, J Xia, S Xu, T She, Y Zhang, Y Sun… - Frontiers in …, 2023 - frontiersin.org
The development and growth of tumors remains an important and ongoing threat to human
life around the world. While advanced therapeutic strategies such as immune checkpoint …

Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

Contributions of nanotechnology to the intraductal drug delivery for local treatment and prevention of breast cancer

JS Passos, VFMC Dartora, GC Salata… - International Journal of …, 2023 - Elsevier
Breast cancer is a major public health problem, affecting millions of people. It is a very
heterogeneous disease, with localized and invasive forms, and treatment generally consists …

Mesoporous silica nanoparticles boost aggressive cancer response to hydrophilic chlorin e6-mediated photodynamic therapy

SA Abdel Gaber, H Stepp, MH Abdel Kader… - Cancer …, 2023 - Springer
Background Chlorin e6 trisodium salt (Ce6) is a newly developed hydrophilic
photosensitizer designed to mediate anticancer photodynamic therapy (PDT). The response …

The relationship between dairy products intake and breast cancer incidence: a meta-analysis of observational studies

Y He, Q Tao, F Zhou, Y Si, R Fu, B Xu, J Xu, X Li… - BMC cancer, 2021 - Springer
Background The effect of dairy products intake on breast cancer (BC) is highly controversial.
This study aims to investigate the relationship between dairy intake and BC incidence …

Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance

J Wang, B Li, M Luo, J Huang, K Zhang… - … and Targeted Therapy, 2024 - nature.com
Ductal carcinoma in situ (DCIS) represents pre-invasive breast carcinoma. In untreated
cases, 25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in …