We used indirect brain mapping with virtual lesion tractography to test the hypothesis that
the extent of white matter tract disconnection due to white matter hyperintensities (WMH) is …

Oxidative stress (OS) is an imbalance between free radicals/ROS and antioxidants, which
evokes a biological response and is an important risk factor for diseases, in both the …

Cerebral perfusion dysfunctions are seen in the early stages of Alzheimer's disease (AD).
We systematically reviewed the literature to investigate the effect of pharmacological and …

Alzheimer's disease (AD) is a multifactorial pathology causing common brain spectrum
disorders in affected patients. These mixed neurological disorders not only include structural …

In critically ill COVID-19 patients, the risk of long-term neurological consequences is just
beginning to be appreciated. While recent studies have identified that there is an increase in …

Background Decreased cerebral blood flow and systemic inflammation during heart failure
(HF) increase the risk for vascular contributions to cognitive impairment and dementia …

Neurodegenerative diseases (ND) share common molecular/cellular mechanisms that
contribute to their progression and pathogenesis. In this sense, we are here proposing new …

Objective To determine the proportional genetic contribution to the variability of cerebral β-
amyloid load in older adults using the classic twin design. Methods Participants (n= 206) …

The relationship between amyloidosis and vasculature in cognitive impairment and
Alzheimer's disease (AD) pathogenesis is increasingly acknowledged. We conducted a …

Background: Heart failure is an epidemiologically relevant disease because of the aging
population and widespread lifestyles that promote it. In addition to the acute event, it is …