[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
Dendrimers as modifiers of inorganic nanoparticles for therapeutic delivery in cancer
The formulation of nanoscale systems with well-defined sizes and shapes is of great interest
in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are …
in applications such as drug and gene delivery, diagnostics and imaging. Dendrimers are …
Safety challenges and application strategies for the use of dendrimers in medicine
X Li, A Naeem, S Xiao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
and entrapment characteristics, are particularly used for the delivery of genes and drugs …
Elaeagnus angustifolia Plant Extract Induces Apoptosis via P53 and Signal Transducer and Activator of Transcription 3 Signaling Pathways in Triple-Negative Breast …
A Fouzat, OJ Hussein, I Gupta, HF Al-Farsi… - Frontiers in …, 2022 - frontiersin.org
Elaeagnus angustifolia (EA) is used as an alternative medicine in the Middle East to
manage numerous human diseases. We recently reported that EA flower extract inhibits cell …
manage numerous human diseases. We recently reported that EA flower extract inhibits cell …
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor
R Padmanabhan, H Kheraldine, I Gupta… - Frontiers in …, 2022 - frontiersin.org
Introduction Immune checkpoint blockade (ICB)-based therapy is revolutionizing cancer
treatment by fostering successful immune surveillance and effector cell responses against …
treatment by fostering successful immune surveillance and effector cell responses against …
[HTML][HTML] Lanatoside C inhibits human cervical cancer cell proliferation and induces cell apoptosis by a reduction of the JAK2/STAT6/SOCS2 signaling pathway
Y Duan, L Chen, J Shao, C Jiang, Y Zhao, Y Li… - Oncology …, 2021 - ncbi.nlm.nih.gov
Cervical cancer is one of the leading causes of cancer-associated mortality in gynecological
diseases and ranks third among female cancers worldwide. Although early detection and …
diseases and ranks third among female cancers worldwide. Although early detection and …
Green immobilized Ag NPs over magnetic Fe3O4 NPs using Pomegranate juice induces apoptosis via P53 and signal transducer and activator of transcription 3 …
M Meng, D Xue - Inorganic Chemistry Communications, 2022 - Elsevier
Herein, we demonstrate the bio-inspired synthesis Ag NPs over surface of magnetic Fe 3 O
4 NPs by using Pomegranate juice (PJ). The Pomegranate juice was used as an eco …
4 NPs by using Pomegranate juice (PJ). The Pomegranate juice was used as an eco …
Mitigating cardiotoxicity of dendrimers: angiotensin-(1-7) via its mas receptor ameliorates PAMAM-induced cardiac dysfunction in the isolated mammalian heart
Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac
contractility and hemodynamics are not known. Herein, we investigated (a) the effect of …
contractility and hemodynamics are not known. Herein, we investigated (a) the effect of …
Aptamer-functionalized dendrimers for targeted cancer therapy
The concept of cancer-based therapy relies upon the improvement of efficacy with a
reduction in toxicity. The chemotherapeutic agents have shown indiscriminate toxic …
reduction in toxicity. The chemotherapeutic agents have shown indiscriminate toxic …