Prevalence and Therapies of Antibiotic-Resistance in Staphylococcus aureus

Y Guo, G Song, M Sun, J Wang… - Frontiers in cellular and …, 2020 - frontiersin.org
Infectious diseases are the second most important cause of human death worldwide;
Staphylococcus aureus (S. aureus) is a very common human pathogenic microorganism that …

Disinfectant resistance in bacteria: Mechanisms, spread, and resolution strategies

C Tong, H Hu, G Chen, Z Li, A Li, J Zhang - Environmental research, 2021 - Elsevier
Disinfectants are widely acknowledged for removing microorganisms from the surface of the
objects and transmission media. However, the emergence of disinfectant resistance has …

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

A Papkou, J Hedge, N Kapel, B Young… - Nature …, 2020 - nature.com
The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread
of a few successful strains, suggesting that some bacteria are genetically pre-disposed to …

Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence

M Alcalde-Rico, S Hernando-Amado, P Blanco… - Frontiers in …, 2016 - frontiersin.org
Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different
levels. Some efflux pumps are constitutively expressed at low levels and contribute to …

Efflux pump inhibitors of clinically relevant multidrug resistant bacteria

A Lamut, L Peterlin Mašič, D Kikelj… - Medicinal Research …, 2019 - Wiley Online Library
Bacterial infections are an increasingly serious issue worldwide. The inability of existing
therapies to treat multidrug‐resistant pathogens has been recognized as an important …

Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus

H Lade, JS Kim - Antibiotics, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

Graphene oxide-based nanocomposites decorated with silver nanoparticles as an antibacterial agent

S Jaworski, M Wierzbicki, E Sawosz, A Jung… - Nanoscale research …, 2018 - Springer
One of the most promising methods against drug-resistant bacteria can be surface-modified
materials with biocidal nanoparticles and nanocomposites. Herein, we present a …

Capsaicin and gut microbiota in health and disease

AE Rosca, MI Iesanu, CDM Zahiu, SE Voiculescu… - Molecules, 2020 - mdpi.com
Capsaicin is a widespread spice known for its analgesic qualities. Although a
comprehensive body of evidence suggests pleiotropic benefits of capsaicin, including anti …

Microbial resistance to antibiotics and effective antibiotherapy

AA Chiș, LL Rus, C Morgovan, AM Arseniu, A Frum… - Biomedicines, 2022 - mdpi.com
Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …

Functional and structural roles of the major facilitator superfamily bacterial multidrug efflux pumps

S Kumar, M Lekshmi, A Parvathi, M Ojha, N Wenzel… - Microorganisms, 2020 - mdpi.com
Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …