Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Sleep timing is controlled by the subtle interplay between circadian and homeostatic
oscillators which, according to their endogenous properties, allow beings to feel …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Daylight is ubiquitous and is crucial for mammalian vision as well as for non-visual input to
the brain via the intrinsically photosensitive retinal ganglion cells (ipRGCs) that express the …

Background Light has powerful effects on mood, sleep, and the circadian system. Humans
evolved in an environment with a clear distinction between day and night, but our modern …

Daylight stems solely from direct, scattered and reflected sunlight, and undergoes dynamic
changes in irradiance and spectral power composition due to latitude, time of day, time of …

The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …

The underlying mechanisms of bright light therapy (BLT) in the prevention of individuals with
subthreshold depression symptoms are yet to be elucidated. The goal of the study was to …

Depressive syndromes are frequent and heterogeneous brain conditions with more than
90% of patients suffering from sleep complaints. Better characterizing this “sleep” domain …

Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …